ALLOCLAMIDE: 0 Products found
Name
ALLOCLAMIDE
EINECS
CAS No.
5486-77-1
Density
Solubility
Melting Point
Formula
C16H23 Cl N2 O2
Boiling Point
Molecular Weight
310.86
Flash Point
Transport Information
Appearance
Safety
Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of Cl and NOx.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms
Benzamide,2-(allyloxy)-4-chloro-N-[2-(diethylamino)ethyl]- (7CI,8CI); Benzamide, 4-chloro-N-[2-(diethylamino)ethyl]-2-(2-propenyloxy)-(9CI); 2-(Allyloxy)-4-chloro-N-[2-(diethylamino)ethyl]benzamide; Alloclamide

History

Formaldehyde was first reported by the Russian chemist Aleksandr Butlerov (1828-1886), but it was conclusively identified by August Wilhelm von Hofmann.

Chemistry

Molecular Structure of Alloclamide (CAS NO.5486-77-1):

IUPAC Name: 4-chloro-N-(2-diethylaminoethyl)-2-prop-2-enoxybenzamide 
Empirical Formula: C16H23ClN2O
Molecular Weight: 310.819 
Index of Refraction: 1.527 
Surface Tension: 38.4 dyne/cm
Density: 1.095 g/cm3 
Flash Point: 215 °C
Enthalpy of Vaporization: 68.76 kJ/mol 
Boiling Point: 431.9 °C at 760 mmHg
Vapour Pressure: 1.16E-07 mmHg at 25°C 
Synonyms of Alloclamide (CAS NO.5486-77-1): Alloclamide ; 2-(Allyloxy)-4-chloro-N-[2-(diethylamino)ethyl]benzamide ; 2-Allyloxy-4-chloro-N-(2-diethylaminoethyl)benzamide

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LDLo intravenous 50mg/kg (50mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: ATAXIA

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Japanese Journal of Pharmacology. Vol. 20, Pg. 1, 1970.
mouse LD50 intraperitoneal 500mg/kg (500mg/kg)   Drugs in Japan Vol. -, Pg. 84, 1990.
mouse LD50 intravenous 65mg/kg (65mg/kg)   Drugs in Japan Vol. 6, Pg. 53, 1982.
mouse LD50 oral > 5gm/kg (5000mg/kg)   Drugs in Japan Vol. -, Pg. 84, 1990.
mouse LD50 subcutaneous 155mg/kg (155mg/kg) BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: ATAXIA
Japanese Journal of Pharmacology. Vol. 20, Pg. 1, 1970.
rat LD50 intraperitoneal 340mg/kg (340mg/kg)   Drugs in Japan Vol. -, Pg. 84, 1990.
rat LD50 intravenous > 25mg/kg (25mg/kg)   Drugs in Japan Vol. -, Pg. 84, 1990.
rat LD50 oral > 3gm/kg (3000mg/kg)   Drugs in Japan Vol. -, Pg. 84, 1990.
rat LD50 subcutaneous > 1gm/kg (1000mg/kg)   Drugs in Japan Vol. -, Pg. 84, 1990.

Safety

Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of Cl and NOx.

Others

 Alloclamide (CAS NO.5486-77-1) is a moderately toxic chemical, flammable. When heated to decomposition it emits toxic fumes of NOx and HCl, so it needed to be stored in low temperature, ventilation, drying and oxidability environmental condition, separated with food ingredients , water, carbon dioxide , dry powder, sand, water mist fire extinguishing can be used if urgency.