Acetyl bromide supplier | CasNO.506-96-7

Name
Acetyl bromide
EINECS 208-061-7
CAS No. 506-96-7
Article Data66
CAS DataBase
Density 1.711 g/cm³
Solubility reacts in water
Melting Point -96 °C
Formula C₂H₃BrO
Boiling Point 75.8 °C at 760 mmHg
Molecular Weight 122.949
Flash Point 49.6 °C
Transport Information UN 1716 8/PG 2
Appearance colorless fuming liquid with a pungent odor
Safety 26-36/37/39-45-9-25
Risk Codes 14-34
Molecular Structure
Hazard Symbols C
Synonyms Acetic acid, bromide;Ethanoyl bromide;
PSA 17.07000
LogP 0.92780

Synthetic route

: 507-02-8
acetyl iodide

: 106-37-6
1.4-dibromobenzene

A: 506-96-7
Acetyl bromide

B: 624-38-4
para-diiodobenzene

Conditions

Conditions	Yield
for 50h; UV-irradiation;	A 95% B 74%
UV-irradiation;	A n/a B 74%

...Expand

: 60-35-5
acetamide

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
With hydrogen bromide at 55 - 85℃; for 1.83333h; Temperature;	94%

: 64-19-7
acetic acid

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
With bromocyane; triphenylphosphine	74%
With phosphorus tribromide
With acetic anhydride; phosphorus tribromide

: CpRe(CO)2(COCH3)(CH3)

: 75-62-7
Bromotrichloromethane

: 201230-82-2
carbon monoxide

A: 74-83-9
methyl bromide

: CpRe(CO)2(CH3)Br

: CpRe(CO)2(COCH3)Br

D: 506-96-7
Acetyl bromide

E: 67-64-1
acetone

Conditions

Conditions	Yield
In dichloromethane-d2 Irradiation (UV/VIS); 355-385 nm light;	A n/a B 43% C 40% D n/a E n/a

...Expand

: 108-86-1
bromobenzene

: 507-02-8
acetyl iodide

A: 591-50-4
iodobenzene

B: 506-96-7
Acetyl bromide

C: 431-03-8
dimethylglyoxal

Conditions

Conditions	Yield
for 50h; UV-irradiation;	A 9% B 20% C 16%
for 50h; UV-irradiation;	A 9% B 20% C 16%

...Expand

: 463-51-4
Ketene

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
With hydrogen bromide; pyrographite

: 14921-00-7
cyanuric bromide

: 64-19-7
acetic acid

A: 506-96-7
Acetyl bromide

B: 108-80-5
isocyanuric acid

Conditions

Conditions	Yield
at 140 - 150℃;

...Expand

: 108-22-5
Isopropenyl acetate

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
With diethyl ether; hydrogen bromide at 10℃;

: 67-66-3
chloroform

: 98556-92-4
acetic acid-(2,4,6,N-tetrabromo-anilide)

: 506-96-7
Acetyl bromide

: 53907-33-8
acetic acid 1-bromo-2-oxo-2-phenyl-ethyl ester

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
at 20℃;

: 855752-10-2
acetic acid-(1-bromo-1-phenoxy-ethyl ester)

A: 506-96-7
Acetyl bromide

B: 122-79-2
Phenyl acetate

Conditions

Conditions	Yield
Erhitzen unter Normaldruck;

: 23128-61-2
2-acetoxy-2-bromo-1,3-diphenyl-propane-1,3-dione

A: 506-96-7
Acetyl bromide

B: 643-75-4
1,3-diphenyl-propane-1,2,3-trione

: 608-36-6
meso-2,3-dibromosuccinic acid

: 108-24-7
acetic anhydride

A: 5926-51-2
bromomaleic anhydride

B: 506-96-7
Acetyl bromide

C: 64-19-7
acetic acid

Conditions

Conditions	Yield
at 120 - 130℃;

...Expand

: 108-24-7
acetic anhydride

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
With hydrogen bromide

: 75-36-5
acetyl chloride

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
With pyridine; tributyltin bromide at 40℃; Thermodynamic data; Equilibrium constant;
With hydrogen bromide at -80℃;
With hydrogen bromide
With aluminium trichloride; hydrogen bromide

: 40796-37-0
Essigsaeure-(α-brombenzyl)ester

A: 506-96-7
Acetyl bromide

B: 100-52-7
benzaldehyde

Conditions

Conditions	Yield
In chloroform-d1 at 20℃; Equilibrium constant;

: 507-02-8
acetyl iodide

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
With pyridine; tributyltin bromide at 40℃; Thermodynamic data; Equilibrium constant;	65 % Spectr.

: 36597-97-4
β,β-dichlorovinyl acetate

A: 506-96-7
Acetyl bromide

B: 34619-29-9
Bromodichloroacetaldehyde

Conditions

Conditions	Yield
With bromine In tetrachloromethane Ambient temperature;

: N-acetyloxy-4-chloro-pyridinium bromide

A: 1121-76-2
4-chloropyridine N-oxide

B: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
In dichloromethane at 24.9℃; Equilibrium constant;

: 10035-10-6, 12258-64-9
hydrogen bromide

: 108-24-7
acetic anhydride

A: 506-96-7
Acetyl bromide

B: 64-19-7
acetic acid

...Expand

: 618-42-8
1-piperidin-1-yl-ethanone

: 7726-95-6
bromine

A: 626-55-1
3-Bromopyridine

B: 625-92-3
3,5-dibromopyridine

C: 506-96-7
Acetyl bromide

D brominated acetyl bromide: brominated acetyl bromide

...Expand

: 10035-10-6, 12258-64-9
hydrogen bromide

: 75-36-5
acetyl chloride

A: 7647-01-0
hydrogenchloride

B: 506-96-7
Acetyl bromide

...Expand

: 7726-95-6
bromine

: 64-19-7
acetic acid

phosphorus: phosphorus

A: 506-96-7
Acetyl bromide

B: 79-08-3
bromoacetic acid

C: 598-21-0
2-Bromoacetyl bromide

...Expand

2-acetoxy-heptene-(1): 2-acetoxy-heptene-(1)

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
With diethyl ether; hydrogen bromide at 0℃;
With chloroform; bromine at -5℃;

2-acetoxy-hexene-(1): 2-acetoxy-hexene-(1)

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
With diethyl ether; hydrogen bromide at 30 - 32℃;

silver salt of/the/ pyruvic acid: silver salt of/the/ pyruvic acid

: 506-96-7
Acetyl bromide

Conditions

Conditions	Yield
With tetrachloromethane; bromine

: 26805-39-0
(Z)-ethyl 3-acetoxybut-2-enoate

: 7726-95-6
bromine

A: 506-96-7
Acetyl bromide

B α-bromo-acetoacetic acid ester: α-bromo-acetoacetic acid ester

C γ-bromo-acetoacetic acid ester: γ-bromo-acetoacetic acid ester

Conditions

Conditions	Yield
at -15℃;

...Expand

2-acetoxy-heptene-(1): 2-acetoxy-heptene-(1)

A: 506-96-7
Acetyl bromide

B: 16339-93-8
1-bromoheptan-2-one

Conditions

Conditions	Yield
With chloroform; bromine at -5℃;

: 67-66-3
chloroform

: 1541-02-2
hept-1-en-2-yl acetate

: 7726-95-6
bromine

A: 506-96-7
Acetyl bromide

B: 16339-93-8
1-bromoheptan-2-one

Conditions

Conditions	Yield
<0;

...Expand

: 646-06-0
1,3-DIOXOLANE

: 506-96-7
Acetyl bromide

: 81777-40-4
2-acetoxyethoxymethyl bromide

Conditions

Conditions	Yield
at 0 - 20℃;	100%
for 2h;	93%
at 0℃;	88%

: 506-96-7
Acetyl bromide

: 78926-09-7
1-tert-butyldimethylsilyloxy-2-phenylethane

: 103-45-7
acetic acid phenethyl ester

Conditions

Conditions	Yield
With tin(II) bromide In dichloromethane for 0.3h; Ambient temperature;	100%

: 506-96-7
Acetyl bromide

: 87783-68-4
α-benzyl-α-(cinnamoylamino)acetonitrile

: 87783-76-4
2-(2-phenylvinyl)-4-benzyl-5-acetamidooxazole

Conditions

Conditions	Yield
With boron trifluoride diethyl etherate In chloroform 0 deg C, 1 h, -> RT, 5 h;	100%

: 111-86-4
n-Octylamine

: 506-96-7
Acetyl bromide

: 7462-62-6
N-octylacetamide

Conditions

Conditions	Yield
With potassium carbonate In methanol; dichloromethane at 25℃; for 1h;	100%

: 506-96-7
Acetyl bromide

: 100-46-9
benzylamine

: 588-46-5
N-(phenylmethyl)acetamide

Conditions

Conditions	Yield
With potassium carbonate In methanol; dichloromethane at 25℃; for 1h;	100%

: 506-96-7
Acetyl bromide

: 299203-18-2
1-triphenylmethoxy-3-phenylpropane

: 122-72-5
3-phenylpropyl acetate

Conditions

Conditions	Yield
In 1,2-dichloro-ethane at 20℃; for 1h;	100%

: 506-96-7
Acetyl bromide

: 54345-41-4
7-methyl-6-octen-2-ynoic acid ethyl ester

: 917-54-4
methyllithium

: 2-acetyl-3,7-dimethylocta-2,6-dienoic acid ethyl ester

Conditions

Conditions	Yield
Stage #1: methyllithium With copper(l) iodide In tetrahydrofuran; diethyl ether at 0℃; for 0.666667h; Stage #2: 7-methyl-6-octen-2-ynoic acid ethyl ester In tetrahydrofuran; diethyl ether at -78℃; Stage #3: Acetyl bromide In tetrahydrofuran; diethyl ether at -78℃; for 4h;	100%

...Expand

: 506-96-7
Acetyl bromide

: 90-97-1
4,4'-dichlorobenzophenone

: 6306-46-3
1-[bromo(4-chlorophenyl)methyl]-4-chlorobenzene

Conditions

Conditions	Yield
In benzene for 3h; Heating / reflux;	100%

: 506-96-7
Acetyl bromide

: 71-48-7, 917-69-1, 5931-89-5, 55881-15-7, 68931-68-0, 68931-69-1, 93029-27-7
cobalt(II) acetate

: cobalt(II) bromide

Conditions

Conditions	Yield
In benzene slow addition of 10% excess of CH3COBr to stirred Co-acetate-solution;; filtration after 30 minutes, washing with benzene, drying in N2-stream at 200°C;;	100%
In benzene slow addition of 10% excess of CH3COBr to stirred Co-acetate-solution;; filtration after 30 minutes, washing with benzene, drying in N2-stream at 200°C;;	100%
In acetic anhydride byproducts: (CH3CO)2O;
In acetic anhydride
In acetic anhydride

: 32981-86-5
10-deacetylbaccatin III

: 506-96-7
Acetyl bromide

: 76-02-8
Trichloroacetyl chloride

: 204124-97-0
7-trichloroacetylbaccatin III

Conditions

Conditions	Yield
Stage #1: 10-deacetylbaccatin III; trifluoroacetyl chloride With pyridine In chloroform at 35℃; for 4h; Stage #2: Acetyl bromide In chloroform at 20℃; for 5h;	100%
Stage #1: 10-deacetylbaccatin III; trifluoroacetyl chloride With pyridine In chloroform at 35℃; for 4h; Stage #2: Acetyl bromide In chloroform at 20℃; for 5h;	100%

...Expand

: 64190-48-3
(S)-3-methyl-4-butanolide

: 506-96-7
Acetyl bromide

: 65527-97-1
(-)-(S)-4-brom-3-methylbutansaeure-ethylester

Conditions

Conditions	Yield
In ethanol at 0 - 20℃; for 2h;	100%
In ethanol at 0 - 20℃;	100%
In ethanol at 0 - 20℃; for 2h;	100%

: 506-96-7
Acetyl bromide

: 1205515-17-8
3-[2-(tert-butyl-dimethyl-silanyloxymethyl)-3-cyclopropylmethyl-5-isopropyl-6-methoxy-pyridin-4-carbonyl]-5-methyl-benzonitrile

: 1205513-12-7
acetic acid 4-(3-cyano-5-methyl-benzoyl)-3-cyclopropylmethyl-5-isopropyl-6-oxo-1,6-dihydro-pyridin-2-ylmethyl ester

Conditions

Conditions	Yield
for 2h; Reflux;	100%

: 10199-34-5, 14056-88-3, 15604-36-1
cis-dichlorobis(triphenylphosphine)platinum(II)

: 506-96-7
Acetyl bromide

: 26026-46-0, 18517-48-1, 16242-58-3
cis-[PtBr2(PPh3)2]

B: 75-36-5
acetyl chloride

Conditions

Conditions	Yield
In dichloromethane at 20 - 25℃; for 0.5h; Glovebox;	A 100% B n/a

...Expand

: 14243-64-2
(triphenylphosphine)gold(I) chloride

: 506-96-7
Acetyl bromide

A: 79384-10-4, 14243-65-3
bromo(triphenylphosphine)gold(I)

B: 75-36-5
acetyl chloride

Conditions

Conditions	Yield
In benzene-d6 at 25℃; for 0.25h; Glovebox;	A 100% B n/a

...Expand

: 506-96-7
Acetyl bromide

: chloro(1,3-bis(2,6-di-i-propylphenyl)imidazol-2-ylidene)gold(I)

: (1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)gold(I)bromide

Conditions

Conditions	Yield
In dichloromethane at 25℃; for 1h; Glovebox;	100%

: 32993-05-8
chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium (II)

: 506-96-7
Acetyl bromide

A: 32993-06-9
[(η5-cyclopentadienyl)Ru(PPh3)2Br]

B: 75-36-5
acetyl chloride

Conditions

Conditions	Yield
In benzene-d6 at 20℃; for 9h; Glovebox;	A 100% B 100%

...Expand

: 87-72-9, 608-45-7, 608-46-8, 608-47-9, 2460-44-8, 6748-95-4, 6763-34-4, 7261-26-9, 7283-06-9, 7283-07-0, 7296-55-1, 7296-56-2, 7296-58-4, 7296-59-5, 7296-60-8, 7296-61-9, 7296-62-0, 7322-30-7, 10257-31-5, 10257-32-6, 10257-33-7, 10257-34-8, 10257-35-9, 19982-83-3, 20242-88-0, 28697-53-2, 36562-42-2, 41546-41-2, 89299-64-9, 107655-34-5, 115794-06-4, 115794-07-5, 130550-15-1, 130606-21-2
D-Xylose

: 506-96-7
Acetyl bromide

: 3068-31-3
1-bromo-2,3,4-tri-O-acetyl-α-D-xylopyranose

Conditions

Conditions	Yield
Stage #1: Acetyl bromide With methanol In acetic acid at 25℃; for 0.25h; Inert atmosphere; Darkness; Stage #2: D-Xylose With acetic acid In acetic acid at 25℃; for 15h; Inert atmosphere;	100%

: 13369-70-5
2-chlorotetrahydrofuran

: 83-25-0
N-phenylmaleimide

: 506-96-7
Acetyl bromide

: 59137-68-7
1-phenyl-2-(tetrahydrofuran-2-yl)ethan-1-one

Conditions

Conditions	Yield
With 1,4-diaza-bicyclo[2.2.2]octane; (2'-dicyclopentylphosphanyl-biphenyl-2-yl)-dimethyl-amine; palladium(II) trifluoroacetate; (1,5-cyclooctadiene)copper(I) hexafluoroacetylacetonate In N,N-dimethyl acetamide at 80℃; for 14h; Temperature; Reagent/catalyst; Solvent;	99.1%

...Expand

: 506-96-7
Acetyl bromide

: benzoic acid 4-trityloxy-butyl ester

: 106842-94-8
4-acetoxybutyl benzoate

Conditions

Conditions	Yield
In 1,2-dichloro-ethane at 20℃; for 1h;	99%

: 506-96-7
Acetyl bromide

: 113548-79-1
2-isopropyl-4-nitro-pyridine-1-oxide

: 1242968-49-5
4-bromo-2-isopropyl-pyridine-1-oxide

Conditions

Conditions	Yield
With acetic acid for 1.5h; Reflux;	99%

: 506-96-7
Acetyl bromide

: 13631-21-5
4-bromo-3-chlorophenol

: 4-bromo-3-chlorophenyl acetate

Conditions

Conditions	Yield
With N,N,N,N,-tetramethylethylenediamine In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;	99%

: 492-62-6
alpha-D-glucopyranose

: 506-96-7
Acetyl bromide

: 108-24-7
acetic anhydride

: 64-19-7
acetic acid

: 572-09-8
2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide

Conditions

Conditions	Yield
With perchloric acid In methanol at 20℃; for 2h;	99%

...Expand

: 506-96-7
Acetyl bromide

: C20H34N2O3

: ethyl (3R,4R,5S)-4-N-acetylamino-5-N,N-diallylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate

Conditions

Conditions	Yield
With pyridine In pyridine; dichloromethane at -10 - 0℃;	98.3%

: 506-96-7
Acetyl bromide

: 57340-80-4
thallium thiophenoxide

A: 934-87-2
S-phenyl thioacetate

B: 882-33-7
diphenyldisulfane

Conditions

Conditions	Yield
In diethyl ether for 1h;	A 98% B 1%

...Expand

: 506-96-7
Acetyl bromide

: 835-79-0
1-(benzyloxy)-2-methoxybenzene

: 613-70-7
2-methoxyphenyl acetate

Conditions

Conditions	Yield
With lithium bromide In dichloromethane at 30 - 35℃; for 6h; Inert atmosphere; regioselective reaction;	98%

: 506-96-7
Acetyl bromide

: 101306-31-4
benzyl cinnamyl ether

A: 140-11-4
Benzyl acetate

B: 4392-24-9
Cinnamyl bromide

Conditions

Conditions	Yield
With lithium bromide In dichloromethane at 30 - 35℃; for 6h; Inert atmosphere;	A 98% B n/a

...Expand

: 506-96-7
Acetyl bromide

: 113209-88-4
2‐methyl‐4‐nitro‐5‐fluoropyridine 1‐oxide

: 2‐methyl‐4‐bromo‐5‐fluoropyridine 1‐oxide

Conditions

Conditions	Yield
	98%

: 506-96-7
Acetyl bromide

: 87633-45-2
5-Hydroxy-2-methoxybenzylalkohol

: 81860-94-8
(3-Brommethyl-4-methoxyphenyl)acetat

Conditions

Conditions	Yield
In water at 0 - 5℃; for 48h;	97%

: 506-96-7
Acetyl bromide

: 72017-00-6
Thallous Phenyl Selenide

A: 38447-66-4
acetyl phenyl selenide

B: 1666-13-3
diphenyl diselenide

Conditions

Conditions	Yield
In diethyl ether for 1h;	A 97% B 1%

...Expand

: 506-96-7
Acetyl bromide

: Trimethyl-(4-phenyl-cyclohexyloxy)-silane

: 5445-95-4, 68285-52-9, 55122-66-2
trans-4-phenylcyclohexyl acetate

Conditions

Conditions	Yield
With tin(II) bromide In dichloromethane for 0.333333h; Ambient temperature;	97%

Acetyl bromide Chemical Properties

IUPAC Name: Acetyl bromide
Molecular Formula: C₂H₃BrO
Molecular Weight: 122.95 g/mol
SMILES: C(C)(=O)Br
InChI: InChI=1/C2H3BrO/c1-2(3)4/h1H3
EINECS: 208-061-7
Product Categories: Pharmaceutical Intermediates; Acid Halides; Carbonyl Compounds; Organic Building Blocks
Water Solubility: REACTS
Sensitive: Moisture Sensitive
Index of Refraction: 1.443
Molar Refractivity: 19.07 cm³
Molar Volume: 71.8 cm³
Polarizability: 7.56×10^-24cm³
Surface Tension: 30.5 dyne/cm
Density: 1.711 g/cm³
Flash Point: 49.6 °C
Enthalpy of Vaporization: 31.69 kJ/mol
Boiling Point: 75.8 °C at 760 mmHg
Melting Point: -96 °C
Vapour Pressure of Acetyl bromide (CAS NO.506-96-7): 103 mmHg at 25 °C

Acetyl bromide Uses

Acetyl bromide (CAS NO.506-96-7) can be used in the synthetic process of the Anti-HIV Agent.

Acetyl bromide Production

Acetyl bromide (CAS NO.506-96-7) is an acyl bromide compound. As is expected, it may be prepared by reaction between phosphorus tribromide and acetic acid:
3 CH₃COOH + PBr₃ → 3 CH₃COBr + H₃PO₃

Acetyl bromide Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mammal (species unspecified)	LC50	inhalation	48gm/m3 (48000mg/m3)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(4), Pg. 55, 1974.
mouse	LD50	intraperitoneal	250mg/kg (250mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 20(12), Pg. 52, 1976.

Acetyl bromide Safety Profile

Hazard Codes: Corrosive C
Risk Statements: 14-34
R14: Reacts violently with water.
R34: Causes burns.
Safety Statements: 26-36/37/39-45-9-25
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S9: Keep container in a well-ventilated place.
S25: Avoid contact with eyes.
RIDADR: UN 1716 8/PG 2
WGK Germany: 3
RTECS: AO5955000
F: 9-21
HazardClass: 8
PackingGroup: II
HS Code of Acetyl bromide (CAS NO.506-96-7): 29159080

Acetyl bromide Specification

Acetyl bromide (CAS NO.506-96-7), its Synonyms are Acetic acid, bromide ; Ethanoyl bromide . It is a colorless fuming liquid with a pungent odor.

Product Name

Acetyl bromide

Synthetic route

Acetyl bromide Chemical Properties

Acetyl bromide Uses

Acetyl bromide Production

Acetyl bromide Toxicity Data With Reference

Acetyl bromide Safety Profile

Acetyl bromide Specification

Related Products

Hot Products