Product Name

  • Name

    isothipendyl hydrochloride

  • EINECS
  • CAS No. 1225-60-1
  • Density
  • Solubility
  • Melting Point 215-220 °C
  • Formula C16H19 N3 S . Cl H
  • Boiling Point 421.3°C at 760 mmHg
  • Molecular Weight 321.90
  • Flash Point 208.6°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx, SOx, and HCl.
  • Risk Codes
  • Molecular Structure Molecular Structure of 1225-60-1 (isothipendyl hydrochloride)
  • Hazard Symbols
  • Synonyms 10H-Pyrido[3,2-b][1,4]benzothiazine,10-[2-(dimethylamino)propyl]-, monohydrochloride (8CI);10H-Pyrido[3,2-b][1,4]benzothiazine-10-ethanamine, N,N,a-trimethyl-, monohydrochloride(9CI); Andantol; Andanton; Isothipendyl hydrochloride; Isothipendylmonohydrochloride; NSC 169186; Nilergex; Theruhistin
  • PSA 44.67000
  • LogP 4.50140

Adanton hydrochloride Chemical Properties

 Molecule structure of Adanton hydrochloride (CAS NO.1225-60-1):

IUPAC Name: N,N-Dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine hydrochloride 
Molecular Weight: 321.8681 g/mol
Molecular Formula: C16H20ClN3
Boiling Point: 421.3 °C at 760 mmHg
Flash Point: 208.6 °C
Enthalpy of Vaporization: 67.53 kJ/mol
Vapour Pressure: 2.63E-07 mmHg at 25 °C
H-Bond Donor: 1
H-Bond Acceptor: 3
Rotatable Bond Count: 3
Exact Mass: 321.106646
MonoIsotopic Mass: 321.106646
Topological Polar Surface Area: 19.4
Heavy Atom Count: 21
Complexity: 323
Canonical SMILES: CC(CN1C2=CC=CC=C2SC3=C1N=CC=C3)N(C)C.Cl
InChI: InChI=1S/C16H19N3S.ClH/c1-12(18(2)3)11-19-13-7-4-5-8-14(13)20-15-9-6-10-17-16(15)19;/h4-10,12H,11H2,1-3H3;1H
InChIKey: RQHCFTORMXCNGP-UHFFFAOYSA-N
EINECS: 214-957-9

Adanton hydrochloride Toxicity Data With Reference

1.    

orl-rat LD50:1220 mg/kg

    NIIRDN    Drugs in Japan. Ethical Drugs. 6 (1982),72.
2.    

orl-mus LD50:222 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 8 (1958),489.
3.    

ipr-mus LD50:65 mg/kg

    ARZNAD    Arzneimittel-Forschung. Drug Research. 18 (1968),435.

Adanton hydrochloride Safety Profile

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx, SOx, and HCl.

Adanton hydrochloride Specification

 Adanton hydrochloride (CAS NO.1225-60-1) is also named as 10-(2-Dimethylamino-2-methylethyl)-10H-pyrido(3,2-
b)(1,4)benzothiazine hydrochloride ; 10-(2-Dimethylaminopropyl)-(1)-4-azaphenthiazin hydrochlorid ; 10-(2-Dimethylaminopropyl)-(1)-4-azaphenthiazin hydrochlorid [German] ; 10-(2-Dimethylaminopropyl)-1-azaphenothiazine hydrochloride ; 10-(2-Dimethylaminopropyl)-10H-pyrido(3,2-b)(1,4)benzothiazine hydrochloride ; 10-(2-Dimethylaminopropyl)-9-thia-1,10-diazaanthracene hydrochloride ; 10H-Pyrido(3,2-b)(1,4)benzothiazine, 10-(2-(dimethylamino)propyl)-, monohydrochloride ; Adantol ; Andantol ; Dimethylamino-isopropyl-thiophenyl-pyridylamin hydrochlorid ; Dimethylamino-isopropyl-thiophenyl-pyridylamin hydrochlorid [German] ; Isothipendyl HCl ; Isothipendyl hydrochloride ; Isothipendyl monohydrochloride ; N-Dimethylaminoisopropylthiophenylpyridylamine hydrochloride ; NSC 169186 ; Nilergex hydrochloride ; Theruhistin ; Theruhistin hydrochloride ; UNII-953AP1LBV8 ; Udantol hydrochloride . Adanton hydrochloride (CAS NO.1225-60-1) is highly toxic. It is flammable. It will produce toxic nitrogen oxide, hydrogen chloride and sulfur oxide fumes when buring. So the storage environment should be ventilate, low-temperature and dry. Keep Adanton hydrochloride (CAS NO.1225-60-1) separate from raw materials of food.

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