Aflatoxin: 0 Products found
Name
Aflatoxin
EINECS
CAS No.
1402-68-2
Density
1.59g/cm3
Solubility
Melting Point
Formula
Boiling Point
612.1°Cat760mmHg
Molecular Weight
0
Flash Point
274.2°C
Transport Information
Appearance
Safety
Confirmed human carcinogen with experimental tumorigenic data. Human poison by ingestion. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. See also various aflatoxins.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms
Aflatoxin;Flavatoxins; Toxins, afla

History

Formaldehyde was first reported by the Russian chemist Aleksandr Butlerov (1828-1886), but it was conclusively identified by August Wilhelm von Hofmann.

Chemistry

Molecular Structure of Aflatoxin (CAS NO.1402-68-2):

Empirical Formula: C17H12O7 
Molecular Weight: 328.273 
Index of Refraction: 1.68 
Surface Tension: 70 dyne/cm
Density: 1.59 g/cm3 
Flash Point: 274.2 °C
Enthalpy of Vaporization: 90.87 kJ/mol 
Boiling Point: 612.1 °C at 760 mmHg
Vapour Pressure: 6.4E-15 mmHg at 25°C 
Synonyms of Aflatoxin (CAS NO.1402-68-2): 1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy- ; 3,4,7aa,10aa-Tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione ; 5-methoxy-3,4,7a,10a-tetrahydro-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione ; (7AR,cis)3,4,7a,10a-tetrahydro-5-methoxy-1H,12H-furo(3',2':4,5)furo(2,3-h)pyrano(3,4-c)chromene-1,12-dione ; 1H,12H-Furo(3',2':4,5)furo(2,3-h)pyrano(3,4-c)(1)benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-  
Classification Code: Human Data ; Mutation data ; Reproductive Effect ; Tumor data                

Production

  Aflatoxin (CAS.NO.1402-68-2)  are naturally occurring mycotoxins that are produced by many species of Aspergillus, a fungus, most notably Aspergillus flavus and Aspergillus parasiticus. Aflatoxins are toxic and among the most carcinogenic substances known.After entering the body, aflatoxins are metabolized by the liver to a reactive intermediate, aflatoxin M1, an epoxide.

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human LDLo oral 229ug/kg/8W (0.229mg/kg) BEHAVIORAL: ANOREXIA (HUMAN

GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE

LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"
Lancet. Vol. 1, Pg. 1061, 1975.
monkey LD50 intramuscular 2020mg/kg (2020mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL" Food and Cosmetics Toxicology. Vol. 14, Pg. 227, 1976.
monkey LD50 oral 1750ug/kg (1.75mg/kg) LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL" Food and Cosmetics Toxicology. Vol. 14, Pg. 227, 1976.
quail LDLo oral 4mg/kg (4mg/kg)   British Poultry Science. Vol. 21, Pg. 29, 1980.

Consensus

 NTP 10th Report on Carcinogens. IARC Cancer Review: Group 1 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 83.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 83.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 83.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210)

Safety

 Confirmed human carcinogen with experimental tumorigenic data. Human poison by ingestion. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. See also various aflatoxins.
 Chronic, subclinical exposure does not cause dramatic symptoms of acute aflatoxin poisoning. However, children are particularly affected by aflatoxin exposure which led to growth retardation and delayed development.  Long-term exposure has also led to the development of liver cancer in high-riskAlloclamide.

Others

 Aflatoxin  (CAS NO.1402-68-2) is a highly toxic chemicals, flammable, while burning it would produce stimulating smoke, so it needed to be stored in low temperature, ventilation, drying and oxidability environmental condition, separated with food ingredients , water, carbon dioxide , dry powder, sand, water mist fire extinguishing can be used if urgency.