Ajmaline-hydrochloride: 0 Products found
Name
Ajmaline-hydrochloride
EINECS
CAS No.
4410-48-4
Density
Solubility
Melting Point
Formula
C20H26N2C2•7ClH
Boiling Point
Molecular Weight
581.70
Flash Point
Transport Information
Appearance
Safety
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx and HCl. See also other Ajmalines.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms

History

Formaldehyde was first reported by the Russian chemist Aleksandr Butlerov (1828-1886), but it was conclusively identified by August Wilhelm von Hofmann.

Chemistry

The Molecular Structure of Ajmaline, hydrochloride (CAS NO.4410-48-4):

Molecular Formula: C20H27ClN2O2
Molecular Weight: 362.893580 g/mol
Nominal Mass: 362 Da
Average Mass: 362.8936 Da
Monoisotopic Mass: 362.176106 Da 
ACD/LogP: 0.78 
Polar Surface Area: 24.94Å2 
Flash Point: 285.2 °C
Enthalpy of Vaporization: 83.4 kJ/mol
Boiling Point: 519.4 °C at 760 mmHg
Vapour Pressure: 1.29E-11 mmHg at 25°C
InChI: InChI=1/C20H26N2O2.ClH/c1-3-10-11-8-14-17-20(12-6-4-5-7-13(12)21(17)2)9-15(16(11)18(20)23)22(14)19(10)24;/h4-7,10-11,14-19,23-24H,3,8-9H2,1-2H3;1H/t10-,11?,14-,15-,16?,17-,18+,19+,20?;/m0./s1
Smiles: C1[C@@]23[C@@H]([C@@H]4[C@@H]5[C@@H]([C@H]([N@@]([C@H]([C@@H]3N(C)c3c2cccc3)C5)[C@@H]14)O)CC)O.Cl

Toxicity

1.    

orl-mus LD50:440 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 127 (1960),163.
2.    

ipr-mus LD50:105 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 127 (1960),163.
3.    

ivn-mus LD50:26 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 127 (1960),163.
4.    

ivn-cat LDLo:2 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 216 (1975),63.

Safety

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx and HCl. See also other Ajmalines.

Others

 Ajmaline, hydrochloride (CAS NO.4410-48-4) is also called as Chlorhydrate de raugalline ; Chlorhydrate de raugalline [French] ; EINECS 224-562-3 ; Ajmalan-17(R),21alpha-diol hydrochloride ; Ajmalan-17,20-diol, hydrochloride, (17R,21alpha)- .