Allorphine: 0 Products found
Name
Allorphine
EINECS
CAS No.
62-67-9
Density
Solubility
Melting Point
Formula
C19H21 N O3
Boiling Point
Molecular Weight
311.41
Flash Point
Transport Information
Appearance
Safety
Poison by intravenous and subcutaneous routes. Moderately toxic by ingestion and other routes. Human systemic effects by parenteral and subcutaneous routes: central nervous system changes, excitement, tremors, hallucinations and distorted perceptions, and antianxiety effects. When heated to decomposition it emits very toxic fumes of NOx. See also ALLYL COMPOUNDS.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms
Morphinan-3,6-diol,7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5a,6a)- (9CI); Morphinan-3,6a-diol, 17-allyl-7,8-didehydro-4,5a-epoxy- (8CI); (-)-Nalorphine; Allorphine; Anarcon;Antorphin; Antorphine; Lethidrone; Letidron; N-Allylnormorphine; NANM; Nallin;Nalline; Nalorphin; Nalorphine; Norfin

History

Formaldehyde was first reported by the Russian chemist Aleksandr Butlerov (1828-1886), but it was conclusively identified by August Wilhelm von Hofmann.

Chemistry

Molecule structure of  Allorphine (CAS NO.62-67-9):

Molecular Weight: 311.37494 g/mol
Molecular Formula: C19H21NO3 
Density: 1.38 g/cm3
Boiling Point: 493.6 °C at 760 mmHg 
Flash Point: 252.3 °C
Index of Refraction: 1.699
Molar Refractivity: 87.05 cm3
Molar Volume: 225.3 cm3
Polarizability: 34.51*10-24 cm3
Surface Tension: 67.8 dyne/cm 
Enthalpy of Vaporization: 80.13 kJ/mol
Vapour Pressure: 1.46E-10 mmHg at 25 °C
XLogP3: 1.9
H-Bond Donor: 2
H-Bond Acceptor: 4
Rotatable Bond Count: 2
Tautomer Count: 3
Exact Mass: 311.152144
MonoIsotopic Mass: 311.152144
Topological Polar Surface Area: 52.9
Heavy Atom Count: 23
Complexity: 549
Defined Atom StereoCenter Count: 5
Canonical SMILES: C=CCN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
Isomeric SMILES: C=CCN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O
InChI: InChI=1S/C19H21NO3/c1-2-8-20-9-7-19-12-4-6-15(22)18(19)23-17-14(21)5-3-11(16(17)19)10-13(12)20/h2-6,12-13,15,18,21-22H,1,7-10H2/t12-,13+,15-,18-,19-/m0/s1
InChIKey: UIQMVEYFGZJHCZ-SSTWWWIQSA-N
EINECS: 200-546-1

Toxicity

1.    

par-hmn TDLo:200 µg/kg:CNS

    PAREAQ    Pharmacological Reviews. 8 (1956),175.
2.    

scu-hmn TDLo:71 µg/kg:PSY

    FEPRA7    Federation Proceedings, Federation of American Societies for Experimental Biology. 15 (1956),442.
3.    

scu-rat LD50:474 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 165 (1967),112.
4.    

ivn-rat LD50:226 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 165 (1967),112.
5.    

orl-mus LD50:1140 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972268.
6.    

ipr-mus LD50:492 mg/kg

    PAREAQ    Pharmacological Reviews. 8 (1956),175.
7.    

scu-mus LD50:500 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 165 (1967),112.
8.    

ivn-mus LD50:127 mg/kg

    AIPTAK    Archives Internationales de Pharmacodynamie et de Therapie. 165 (1967),112.
9.    

par-mus LD50:670 mg/kg

    PAREAQ    Pharmacological Reviews. 8 (1956),175.
10.    

scu-mky LDLo:400 mg/kg

    FEP

Safety

Poison by intravenous and subcutaneous routes. Moderately toxic by ingestion and other routes. Human systemic effects by parenteral and subcutaneous routes: central nervous system changes, excitement, tremors, hallucinations and distorted perceptions, and antianxiety effects. When heated to decomposition it emits very toxic fumes of NOx. See also ALLYL COMPOUNDS.

Others

 Allorphine (CAS NO.62-67-9) is also called 17-Allyl-7,8-didehydro-4,5-alpha-epoxymorphinan-3,6alpha-diol ; 17-allyl-7,8-didehydro-4,5-alpha-epoxy-morphinan-6-alpha-diol ; 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-,(5alpha,6alpha)-morphinan-6-diol ; 7,8-didehydro-4,5-epoxy-17-(2-propenyl)morphinan-3,6-diol ; Acetorfin ; Acetorphine ; Anarcon . Allorphine (CAS NO.62-67-9) is moderate toxic. It is flammable. It will produce toxic nitrogen oxide fumes when buring. So the storage environment should be ventilate, low-temperature and dry. Keep Allorphine (CAS NO.62-67-9) separate from raw materials of food.