Aluminum-Clofibrate: 0 Products found
Name
Aluminum-Clofibrate
EINECS
CAS No.
24818-79-9
Density
g/cm3
Solubility
Melting Point
Formula
C20H21 Al Cl2 O7
Boiling Point
324.1°Cat760mmHg
Molecular Weight
471.29
Flash Point
149.8°C
Transport Information
Appearance
Safety
Moderately toxic by some routes. When heated to decomposition it emits toxic fumes of Cl. See also ALUMINUM COMPOUNDS.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms
Aluminum,bis[2-(4-chlorophenoxy)-2-methylpropanoato-O1,O2]hydroxy-; Aluminum, bis[2-(p-chlorophenoxy)-2-methylpropionato]hydroxy-(8CI); Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, aluminum complex;Alfibrate; Alufibrate; Aluminium clofibrate; Aluminum clofibrate; Atherolip;Atherolipin

History

Formaldehyde was first reported by the Russian chemist Aleksandr Butlerov (1828-1886), but it was conclusively identified by August Wilhelm von Hofmann.

Chemistry

Molecule structure of Aluminum Clofibrate (CAS NO.24818-79-9):

IUPAC Name: Bis[[2-(4-chlorophenoxy)-2-methylpropanoyl]oxy]aluminum hydrate 
Molecular Weight: 472.272018 g/mol
Molecular Formula: C20H22AlCl2O7
H-Bond Donor: 1
H-Bond Acceptor: 7
Rotatable Bond Count: 10
Exact Mass: 471.055797
MonoIsotopic Mass: 471.055797
Topological Polar Surface Area: 72.1
Heavy Atom Count: 30
Complexity: 509
Canonical SMILES: CC(C)(C(=O)O[Al]OC(=O)C(C)(C)OC1=CC=C(C=C1)Cl)OC2=CC=C(C=C2)Cl.O
InChI: InChI=1S/2C10H11ClO3.Al.H2O/c2*1-10(2,9(12)13)14-8-5-3-7(11)4-6-8;;/h2*3-6H,1-2H3,(H,12,13);;1H2/q;;+2;/p-2
InChIKey: RSMSFENOAKAUJU-UHFFFAOYSA-L
EINECS: 246-477-0

Uses

 Aluminum Clofibrate (CAS NO.24818-79-9) is used as Intermediates for pharmaceutical Clofibrate.

Toxicity

1.    

ipr-rat LD50:3300 mg/kg

    JJPAAZ    Japanese Journal of Pharmacology. 23 (1973),281.
2.    

scu-rat LD50:5100 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),237.
3.    

ipr-mus LD50:3300 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),237.
4.    

scu-mus LD50:5850 mg/kg

    NIIRDN    “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),237.

Safety

Moderately toxic by some routes. When heated to decomposition it emits toxic fumes of Cl. See also ALUMINUM COMPOUNDS.

Others

 Aluminum Clofibrate (CAS NO.24818-79-9) is also named as Alfibrate ; Alufibrate ; Aluminii clofibras ; Aluminii clofibras [INN-Latin] ; Atherolip ; Bis(2-(p-chlorophenoxy)-2-methylpropionato)hydroxyaluminum ; Clofibrate d'aluminium ; Clofibrate d'aluminium [INN-French] ; Clofibrato de aluminio ; Clofibrato de aluminio [INN-Spanish] ; Hydroxybis(2-(p-chlorophenoxy)isobutyric acid) aluminum ; Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-, aluminum complex ; UNII-56203T2K2X ; Aluminum, bis(2-(4-chlorophenoxy)-2-methylpropanoato-O1,O2)hydroxy- (9CI) ; Aluminum, bis(2-(4-chlorophenoxy-kappaO)-2-methylpropanoateo-kappaO)hydroxy- ; Aluminum, bis(2-(p-chlorophenoxy)-2-methylpropionato)hydroxy- (8CI) .