Amino-α-carboline supplier | CasNO.26148-68-5

Name
2-AMINO-9H-PYRIDO[2,3-B]INDOLE
EINECS
CAS No. 26148-68-5
Article Data1
CAS DataBase
Density 1.393g/cm³
Solubility
Melting Point 194-196
Formula C11H9 N3
Boiling Point 440.9°Cat760mmHg
Molecular Weight 183.213
Flash Point 250.7°C
Transport Information
Appearance Crystalline Solid
Safety Suspected carcinogen with experimental carcinogenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 1H-Pyrido[2,3-b]indol-2-amine(9CI); 9H-Pyrido[2,3-b]indole, 2-amino- (8CI); 2-Amino-9H-pyrido[2,3-b]indole;2-Amino-a-carboline; 9H-1,9-Diazafluoren-2-amine;AaC; AaC
PSA 54.70000
LogP 2.87950

Amino-α-carboline Chemical Properties

IUPAC Name: 9H-pyrido[2,3-b]indol-2-amine
Molecular Weight: 183.20926 g/mol
Molecular Formula: C₁₁H₉N₃
Density: 1.393 g/cm³
Melting Point: 194-196 °C
Boiling Point: 440.9 °C at 760 mmHg
Flash Point: 250.7 °C
Appreance: crystalline Solid
Molar Volume: 131.4 cm³
Polarizability: 23.26*10^-24cm³
Surface Tension: 81 dyne/cm
Enthalpy of Vaporization: 69.81 kJ/mol
Vapour Pressure: 5.68E-08 mmHg at 25 °C
XLogP3: 2.6
H-Bond Donor: 2
H-Bond Acceptor: 2
Tautomer Count: 6
Exact Mass: 183.079647
MonoIsotopic Mass: 183.079647
Topological Polar Surface Area: 54.7
Heavy Atom Count: 14
Complexity: 219
Canonical SMILES: C1=CC=C2C(=C1)C3=C(N2)N=C(C=C3)N
InChI: InChI=1S/C11H9N3/c12-10-6-5-8-7-3-1-2-4-9(7)13-11(8)14-10/h1-6H,(H3,12,13,14)
InChIKey: FJTNLJLPLJDTRM-UHFFFAOYSA-N
Product Categories: Detergents; Mutagenesis Research Chemicals

Amino-α-carboline Uses

A pyrolysate that exhibited mutagenic activity toward Salmonella typhimurium TA98 and TA100 from the pyrolytic products of soybean globulin.

Amino-α-carboline Toxicity Data With Reference

1.	sce-hmn:lym 4000 µg/L	MUREAV Mutation Research. 77 (1980),65.
2.	mmo-sat 1 µg/plate ABCHA6 43,1155,79
3.	mma-sat 1 µg/plate	CALEDQ Cancer Letters (Shannon, Ireland). 10 (1980),141.
4.	dnr-bcs 10 µL/plate ABCHA6 45,2031,81
5.	slt-dmg-orl 400 ng/kg	JJCREP Japanese Journal of Cancer Research (Gann). 76 (1985),468.
6.	orl-mus TDLo:37,600 mg/kg/98W-C:CAR	EVHPAZ EHP, Environmental Health Perspectives. Subseries of DHEW Publications. 67 (1986),129.
7.	orl-mus TD:50,424 mg/kg/82W-C:CAR	CRNGDP Carcinogenesis. 5 (1984),815.

Amino-α-carboline Consensus Reports

IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 (1986),p. 245.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Amino-α-carboline Safety Profile

Suspected carcinogen with experimental carcinogenic data. Human mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
Hazard Codes: Xi
RIDADR: 2811
Hazard Note: Irritant/Mutagen
HazardClass: 6.1(b)
PackingGroup: III

Amino-α-carboline Specification

Amino-α-carboline (CAS NO.26148-68-5) is also named 2-Amino-9h-pyrido[2,3-b]indole ; AC ; 1h-Pyrido(2,3-b)indol-2-amine ; 2-amino-alpha-carboline ; 2-amino-9h-pyridol[2,3-beta]indole ; 2-amino-9h-pyridol(2,3-b)indole . Amino-α-carboline (CAS NO.26148-68-5) is a kind of toxic substances. It is flammable. Amino-α-carboline (CAS NO.26148-68-5) will produce toxic nitrogen oxide fumes when buring. So the storage environment should be ventilate, low-temperature and dry.

Product Name

2-AMINO-9H-PYRIDO[2,3-B]INDOLE