Product Name

  • Name

    PUROMYCIN AMINONUCLEOSIDE

  • EINECS 200-388-3
  • CAS No. 58-60-6
  • Article Data11
  • CAS DataBase
  • Density 1.7 g/cm3
  • Solubility H2O: 50 mg/mL, clear, slightly yellow
  • Melting Point 235℃ (Decomposition)
  • Formula C12H18 N6 O3
  • Boiling Point 595.6 °C at 760 mmHg
  • Molecular Weight 294.313
  • Flash Point 314 °C
  • Transport Information
  • Appearance
  • Safety An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes 48/22
  • Molecular Structure Molecular Structure of 58-60-6 (PUROMYCIN AMINONUCLEOSIDE)
  • Hazard Symbols Xi,Xn
  • Synonyms 3'-Amino-3'-deoxy-N6,N6-dimethyladenosine;6-(Dimethylamino)-9-(3-amino-3-deoxy-b-D-ribofuranosyl)purine; 6-Dimethylamino-9-(3-amino-3-deoxyribosyl)purine;9-(3-Amino-3-deoxy-b-D-ribofuranosyl)-6-(dimethylamino)-9H-purine; Aminonucleoside;Aminonucleoside puromycin; NSC 3056; PANS; Puromycin, aminonucleoside; SAN;Stylomycin aminonucleoside
  • PSA 122.55000
  • LogP -0.82950

Aminonucleoside puromycin Chemical Properties

Molecule structure of Aminonucleoside puromycin (CAS NO.58-60-6):

IUPAC Name: 4-Amino-2-[6-(dimethylamino)purin-9-yl]-5-(hydroxymethyl)oxolan-3-ol 
Molecular Weight: 294.30972 g/mol
Molecular Formula: C12H18N6O3 
Density: 1.7 g/cm3 
Boiling Point: 595.6 °C at 760 mmHg 
Flash Point: 314 °C
Index of Refraction: 1.775
Molar Refractivity: 71.91 cm3
Molar Volume: 172.1 cm3
Polarizability: 28.5×10-24 cm3
Surface Tension: 73.2 dyne/cm 
Enthalpy of Vaporization: 93.34 kJ/mol
Vapour Pressure: 4.93E-15 mmHg at 25 °C 
Storage Temp.: 2-8 °C
Solubility: H2O: 50 mg/mL, clear, slightly yellow
XLogP3: -0.5
H-Bond Donor: 3
H-Bond Acceptor: 8
Rotatable Bond Count: 3
Exact Mass: 294.144038
MonoIsotopic Mass: 294.144038
Topological Polar Surface Area: 123
Heavy Atom Count: 21 
Complexity: 373
Canonical SMILES: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)N)O
InChI: InChI=1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3
InChIKey: RYSMHWILUNYBFW-UHFFFAOYSA-N
EINECS: 200-388-3

Aminonucleoside puromycin Toxicity Data With Reference

1.    

dni-hmn:lng 6 mg/L

     JCLLAX    Journal of Cellular Physiology. 81 (1973),71.
2.    

oms-hmn:lng 6 mg/L

     JCLLAX    Journal of Cellular Physiology. 81 (1973),71.
3.    

scu-rat TDLo:45 mg/kg (female 8-10D post):TER

     NPRNAY    Nephron. 3 (1966),344.

Aminonucleoside puromycin Consensus Reports

Reported in EPA TSCA Inventory.

Aminonucleoside puromycin Safety Profile

Hazard Codes: IrritantXi
WGK Germany: 3
RTECS: AU7337000
F: 10-21
An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Aminonucleoside puromycin Specification

 Aminonucleoside puromycin (CAS NO.58-60-6) is also named as 3'-Amino-3'-deoxy-N6,N6-dimethyladenosine ; 4-26-00-03697 (Beilstein Handbook Reference) ; 6-Dimethylamino-9-(3'-ribosylamine)purine ; ARDMA ; Aminonucleoside ; BRN 0093902 ; NSC 3056 ; Puromycin aminonucleoside ; SAN ; Stylomycin aminonucleoside . Aminonucleoside puromycin (CAS NO.58-60-6) is toxic. It is flammable. It will produce toxic nitrogen oxide fumes when buring. So the storage environment should be ventilate, low-temperature and dry.

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