Furo[2,3-c]pyridine-2-carboxylic acid

The Furo[2, 3-c]pyridine-2-carboxylic acid has CAS registry number 112372-15-3. This chemical's molecular formula is C₈H₅NO₃ and molecular weight is 163.132. What's more, its systematic name is Furo[2, 3-c]pyridine-2-carboxylic acid.

Physical properties about Furo[2, 3-c]pyridine-2-carboxylic acid are: (1)ACD/LogP: 0.50; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2; (4)ACD/LogD (pH 7.4): -2; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 4; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 63.33 Å²; (13)Index of Refraction: 1.661; (14)Molar Refractivity: 41.416 cm³; (15)Molar Volume: 112.097 cm³; (16)Polarizability: 16.419×10^-24 cm³; (17)Surface Tension: 67.546 dyne/cm; (18)Density: 1.455 g/cm³; (19)Flash Point: 167.287 °C; (20)Enthalpy of Vaporization: 63.091 kJ/mol; (21)Boiling Point: 352.997 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25 °C.

Preparation of Furo[2, 3-c]pyridine-2-carboxylic acid: this chemical is prepared by Furo[2, 3-c]pyridine-2-carbonitrile by heating. The reaction needs reagent KOH and solvent Ethanol. The reaction time is 2 hours. The yield is about 95 %.

Uses of Furo[2, 3-c]pyridine-2-carboxylic acid: it is used to produce other chemicals. For example, it is used to produce Furo[2, 3-c]pyridine-2-carboxylic acid ethyl ester by heating. The reaction needs reagent H₂SO₄. The reaction time is 15 hours. The yield is about 78 %.

You can still convert the following datas into molecular structure:
(1) SMILES: OC(=O)c1cc2ccncc2o1
(2) InChI: InChI=1/C8H5NO3/c10-8(11)6-3-5-1-2-9-4-7(5)12-6/h1-4H,(H,10,11)
(3) InChIKey: WMPIDXCJMDIDQY-UHFFFAOYAF