N-CHLOROACETYLGLYCINE

The Glycine,N-(2-chloroacetyl)- is an organic compound with the formula C₄H₆ClNO₃. The IUPAC name of this chemical is 2-[(2-chloroacetyl)amino]acetic acid. With the CAS registry number 6319-96-6, it is also named as N-(Chloroacetyl)glycine. The product's categories are API Intermediates; A - H; Amino Acids; Modified Amino Acids. Besides, it should be stored in a dark closed and cool place.

Physical properties about Glycine,N-(2-chloroacetyl)- are: (1)ACD/LogP: -1.04; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 1; (5)ACD/KOC (pH 7.4): 1; (6)#H bond acceptors: 4; (7)#H bond donors: 2; (8)#Freely Rotating Bonds: 3; (9)Polar Surface Area: 46.61 Å²; (10)Index of Refraction: 1.486; (11)Molar Refractivity: 30.61 cm³; (12)Molar Volume: 106.5 cm³; (13)Polarizability: 12.13×10^-24cm³; (14)Surface Tension: 50.9 dyne/cm; (15)Density: 1.422 g/cm³; (16)Flash Point: 214.8 °C; (17)Enthalpy of Vaporization: 75.36 kJ/mol; (18)Boiling Point: 431.6 °C at 760 mmHg; (19)Vapour Pressure: 1.17E-08 mmHg at 25°C.

Preparation: this chemical can be prepared by chloroacetyl chloride and glycine. This reaction will need reagent aq. NaOH solution.

Uses of Glycine,N-(2-chloroacetyl)-: it can be used to produce (-)-N-(Chloroacetyl)glycin-((1R,3R,4S)-menthyl)ester at temperature of 110 °C. It will need reagent p-toluenesulfonic acid monohydrate and solvent toluene with reaction time of 16 hours. The yield is about 88%.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: ClCC(=O)NCC(=O)O
(2)InChI: InChI=1/C4H6ClNO3/c5-1-3(7)6-2-4(8)9/h1-2H2,(H,6,7)(H,8,9)
(3)InChIKey: DLDTUYIGYMNERN-UHFFFAOYAA
(4)Std. InChI: InChI=1S/C4H6ClNO3/c5-1-3(7)6-2-4(8)9/h1-2H2,(H,6,7)(H,8,9)
(5)Std. InChIKey: DLDTUYIGYMNERN-UHFFFAOYSA-N