JACOBINE Chemical Properties
Jacobine(6870-67-3)'s molecular formula is
C18H25NO6 and its formula weight is 351.44.
Jacobine(6870-67-3)'s chemical synonyms are Jacobine(6870-67-3);(15R,20S)-15,20-Dihydro-15,20-epoxy-12-hydroxysenecionan-11,16-dione;(20S)-15α,20-Epoxy-15,20-dihydro-12-hydroxysenecionan-11,16-dione;NSC-89936.
The molecular structure of j
acobine(6870-67-3):
JACOBINE Toxicity Data With Reference
1. | | sln-dmg-par 20 µmol/L | | ZEVBA5 Zeitschrift fuer Verebungslehre. 91 (1960),74. |
2. | | dns-rat:lvr 1 µmol/L | | CNREA8 Cancer Research. 45 (1985),3125. |
3. | | ivn-mus LD50:77 mg/kg | | JPETAB Journal of Pharmacology and Experimental Therapeutics. 75 (1942),69. |
JACOBINE Consensus Reports
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 10 (1976),p. 275.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.
JACOBINE Safety Profile
Poison by intravenous route. Questionable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.