AGOMELATINE-

AGOMELATINE-

AGOMELATINE-

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1 Kilogram

Negotiable

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,T/T,

Keywords

AGOMELATINE 138112-76-2 AGOMELATINE

Quick Details

  • Appearance:White to offwhite crystalline powder
  • Application:Intermediate
  • PackAge:bottle/drum or customer's request
  • ProductionCapacity:1|Metric Ton|Month
  • Storage:N/A
  • Transportation:---

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Details:

AGOMELATINE Basic information

Product Name: AGOMELATINE
Synonyms: AGOMELATINE;n-(2-(7-methoxy-1-naphthalenyl)ethyl)-acetamid;n-(2-(7-methoxy-1-naphthalenyl)ethyl)acetamide;n-(2-(7-methoxynaphth-1-yl)ethyl)acetamide;S20098,N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide;S 20098;AGOMELATIN;Acetamide, N-(2-(7-methoxy-1-naphthalenyl)ethyl)-
CAS: 138112-76-2
MF: C15H17NO2
MW: 243.30098
EINECS:  
Product Categories: Aromatics Compounds;Aromatics;Neurochemicals;APIS;API;Agomelatine;Valdoxan, Melitor, Thymanax
Mol File: 138112-76-2.mol
AGOMELATINE Structure
 
AGOMELATINE Chemical Properties
mp  107-109°C
storage temp.  -20°C Freezer
CAS DataBase Reference 138112-76-2(CAS DataBase Reference)
 
Safety Information
Hazard Codes  N
Risk Statements  50
Safety Statements  61
MSDS Information
 
 
AGOMELATINE Usage And Synthesis
Chemical Properties White Solid
Usage Agomelatine is an antidepressant drug. It is classified as a norepinephrine-dopamine disinhibitor (NDDI) due to its antagonism of the 5-HT2C receptor. Activation of 5-HT2C receptors by serotonin inhibits dopamine and norepinephrine release. Antagonism of
Usage Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively.

 

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