N-(Hydroxymethyl)phthalimide 118-29-6

Superiority:

Product Name: N-(Hydroxymethyl)phthalimide
Synonyms: oxymethylphthalimide;Phthalimide, N-(hydroxymethyl)-;Phthalimidomethyl alcohol;phthalimidomethylalcohol;4-(Hydroxymethyl)phthalimide, 97%;1H-Isoindole-1,3(2H)-dione, 2-(hydroxymethyl)-;N-Hydroxymethylphthalimide, 97 %;N-(Hydroxymethyl)phthalimide, 98+%
CAS: 118-29-6
MF: C9H7NO3
MW: 177.16
EINECS: 204-241-4
Product Categories: pharmacetical;N-Substituted Maleimides, Succinimides & Phthalimides;N-Substituted Phthalimides;intermediates;fine chemicals
Mol File: 118-29-6.mol

N-(Hydroxymethyl)phthalimide Chemical Properties
Melting point  147-149 °C(lit.)
Boiling point  309.06°C (rough estimate)
density  1.3312 (rough estimate)
refractive index  1.5200 (estimate)
storage temp.  Store below +30°C.
pka 13.17±0.10(Predicted)
form  Fine Crystalline Powder
color  White
BRN  140946
InChIKey MNSGOOCAMMSKGI-UHFFFAOYSA-N
CAS DataBase Reference 118-29-6(CAS DataBase Reference)
NIST Chemistry Reference 1H-isoindole-1,3(2h)-dione, 2-(hydroxymethyl)-(118-29-6)
EPA Substance Registry System N-(Hydroxymethyl)phthalimide (118-29-6)
Safety Information
Safety Statements  22-24/25
WGK Germany  3
RTECS  TI5270000
TSCA  Yes
HS Code  29251995

N-(Hydroxymethyl)phthalimide Usage And Synthesis
Chemical Properties white crystalline powder
Definition ChEBI: A primary alcohol comprising phthalimide carrying an N-hydroxymethyl substituent.
Preparation To a flask equipped with a mechanical stirrer and condenser is added 511 gm (3.47 moles) of phthalimide, 260 ml of 40% formalin (3.47 moles), and 1750 ml of water. The mixture is refluxed for about 5-10 min or until a clear solution results (if any insoluble material remains, it is first filtered). Then the mixture is cooled for several hours. The resulting product is filtered with suction, washed with cold water, and air-dried to afford 594 gm (96%), m.p. 137-141°C.
NOTE: The product should not be oven-dried since it decomposes with the loss of formaldehyde. Recrystallization of the product from ethanol affords 94% recovery of the original material with the same melting point range.