562-10-7 Doxylamine succinate doxylamine hydrogen succinate
Name | Doxylamine succinate |
CAS No. | 562-10-7 |
EINECS | 209-228-7 |
MF | C21H28N2O5 |
MW | 388.46 |
MP | 95-98°C |
Storage temp. | Refrigerator |
Purity | 99% min |
Usage | H1 Histamine receptor antagonist. Antihistaminic; sedative; hypnotic. |
Test Items |
Specifications |
Results |
Appearance |
White or almost white crystalline powder |
Conform |
Solubility |
Very soluble in water, freelysoluble in alcohol |
Conform |
Identification |
1) Melting range:103℃-108℃ 2) Ultraviolet absorption: UVmax=262.0nm 3) Organic Nitrogenous Bases 4) Succinic acid melting range:184℃-188℃ |
105℃ 262.0 nm
Conform
186℃-188℃ |
Loss on drying |
≤0.5% |
0.3% |
Residue on ignition |
≤0.1% |
0.1% |
Related substances(GC) |
Total impurities≤2.0% Single impurity≤1.0% |
1.9% 1.0% |
Residual solvents |
Diethyl ether≤0.5% Acetone≤0.5% Iso-propyl ether≤0.5% Toluene≤0.1% |
0.4% 0.4% 0.4% 0.1% |
Assay |
98.0%-101.0% (Calculated on anhydrous substance) |
99.2% |
Conclusion |
Conform to the USP29 |
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