OMEPRAZOLE

OMEPRAZOLE

OMEPRAZOLE

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0 Metric Ton

Negotiable

  • Min.Order :0 Metric Ton
  • Purity: 98% Min

Keywords

ZOLTUM (S)-OMEPRAZOLE 2-[(4-METHOXY-3,5-DIMETHYLPYRID-2-YL)-METHYLSULFO]-5-METHOXYBENZIMIDAZOLE

Quick Details

  • Appearance:white powder
  • Application:intermediates
  • PackAge:aluminium bag
  • ProductionCapacity:|Metric Ton|Day
  • Storage:keep in dry and ventilated place
  • Transportation:By sea/By air

Superiority:

Description: Omeprazole is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are at high risk. Omeprazole is a proton pump inhibitor and as such blocks the release of stomach acid.

Details:

Synonym: Omeprazole, H 168-68, Losec, Prilosec, Zegerid

IUPAC/Chemical Name: 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole

SMILES Code: O=S(C1=NC2=CC=C(OC)C=C2N1)CC3=NC=C(C)C(OC)=C3C

Omeprazole Basic information

Product Name:

Omeprazole

Synonyms:

1h-benzimidazole,5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulf;2-Chloromethyl-3,5-dinmethyl-4-methoxypyridine;5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazol;audazol;aulcer;belmazol;ceprandal;elgam

CAS:

73590-58-6

MF:

C17H19N3O3S

MW:

345.42

EINECS:

201-212-8

Product Categories:

Drug bulk;Active Pharmaceutical Ingredients;Omeprazole;Intermediates & Fine Chemicals;Pharmaceuticals;API's;ATPase;Metabolite Reference Standard;Isotopically Labeled Pharmaceutical Reference Standard;OSMITROL;Other APIs;Digestive System

 

Omeprazole Chemical Properties

mp

156°C

storage temp.

2-8°C

solubility

H2O: 0.5 mg/mL

Merck

6845

Stability:

Stable, but hygroscopic and photosensitive. Incompatible with strong oxidizing agents. Store in the dark.

CAS DataBase Reference

73590-58-6(CAS DataBase Reference)

Safety Information

Hazard Codes

Xi,T,F

Risk Statements

36/37/38-39/23/24/25-23/24/25-11

Safety Statements

26-36-37/39-45-36/37-16-7

WGK Germany

2

RTECS

DD9087000

Hazardous Substances Data

73590-58-6(Hazardous Substances Data)

Omeprazole Usage And Synthesis

Chemical Properties

White Crystalline Solid

Usage

Binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative

diuretic, sweetener, diagnostic aid

A selective proton pump and CYP inhibitor

Omeprazole Pellets are used in the treatment of Gastroesophageal reflux disease (GERD): A condition in which backward flow of acid from the stomach causes heartburn and injury of the food pipe (esophagus)

Biological Activity

H + ,K + -ATPase inhibitor (IC 50 = 5.8 μ M) that displays antisecretory and antiulcer activity. Inhibits gastric acid secretion (IC 50 = 0.16 μ M for histamine-induced acid formation) and reduces gastric lesion formation induced by a variety of ulcerative stimuli. Antibacteral against Helicobacter pylori in vitro . Also inhibits CYP2C19, CYP2C9 and CYP3A (K i values are 3.1, 40.1 and 84.4 μ M respectively) and blocks swelling-dependent chloride channels (ICIswell).

 

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