188627-80-7 Eptifib...

188627-80-7 Eptifibatide

188627-80-7 Eptifibatide

Min.Order / FOB Price:Get Latest Price

1 Kilogram

FOB Price: USD 1000.0000

  • Min.Order :1 Kilogram
  • Purity: 99%
  • Payment Terms : L/C,T/T

Keywords

188627-80-7 Eptifibatide C35H49N11O9S2

Quick Details

  • Appearance:white powder
  • Application:pharma
  • PackAge:as clients needs
  • ProductionCapacity:1|Metric Ton|Day
  • Storage:RT
  • Transportation:sea

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Details:

Eptifibatide Chemical Properties 
CAS DataBase Reference 188627-80-7 
 Safety Information 
 MSDS Information 
 Eptifibatide Usage And Synthesis 
Description Eptifibatide is a kind of synthetic cyclic hexapeptide consisting of 6 amino acids and 1 mercaptopropionyl residue. It is capable of binding to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets and inhibiting the platelet aggregation, thus blocking the binding of the fibrinogen, von Willebrand factor and other adhesive ligands. It is indicated for the treatment of acute coronary syndrome (ACS) and Percutaneous coronary intervention (PCI). It is able to reduce the risk of acute cardiac ischemic events in patients with unstable angina or non-ST segment-elevation myocardial infection. It is often used in combination with aspirin or clopidogrel and heparin. It can be manufactured through solution-phase peptide synthesis, and can be purified by preparative reverse-phase liquid chromatography and lyophilization.  
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Uses A Arginin-glycin-aspartat-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events. 
Definition ChEBI: A synthetic homodetic cyclic peptide comprising Nalpha-(3-sulfanylpropanoyl)homoarginyl, glycyl, aspartyl, tryptophyl, prolyl and cysteinamide residues connected in sequence and cyclised via a disulf de bond. Derived from a protein found in the venom of the southeastern pygmy rattlesnake, Sistrurus miliarus barbouri, eptifibatide is an anti-coagulant that inhibits platelet aggregation by selectively blocking the platelet glycoprotein IIb/I Ia receptor, so preventing the binding of fibrinogen, von Willebrand factor, and other adhesive ligands. It is used in the management of unstable angina and in patients undergoing coronary angioplasty and stenting procedures. 
 
 
 
 
 

 

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