Isopropenylboronic acid pinacol ester Chemical Properties
Melting point 157-161 °C
Boiling point 47-49 °C (9 mbar)
density 0.894
refractive index 1.4320
Fp 42 °C
storage temp. 2-8°C
form Liquid
color Clear, colorless to brown
InChIKey SVSUYEJKNSMKKW-UHFFFAOYSA-N
Safety Information
Hazard Codes Xi
Risk Statements 10-36/37/38-43
Safety Statements 16-26-36/37
RIDADR UN 1993
HazardClass IRRITANT
PackingGroup Ⅲ
MSDS Information
Isopropenylboronic acid pinacol ester Usage And Synthesis
Description Isopropenylboronic acid pinacol ester is a versatile ester reagent used for palladium-catalyzed Suzuki-Miyaura cross-coupling processes, inverse-electron-demand Diels-Alder reaction, Simmons-Smith cyclopropanation reaction, polyene cyclization, stereoselective aldol reactions, Grubbs cross-metathesis reaction, intramolecular Suzuki-Miyaura reaction, Stereoselective cross-metathesis, dipolar cycloaddition, iodosulfonylation, asymmetric conjugate addition and intramolecular hydroacylation and preparation of various therapeutic kinase and enzymatic inhibitors1. It can be used as an intermediate in the synthesis of variety of cyclic and acyclic organic compounds. It is also shown that the α-Substituted Allyl/Croty of this compound can be used for highly Diastereo- and Enantioselective allylboration of aldehydes2.
Sources # lang=en®ion=US
# I821825
Uses suzuki reaction