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Keywords
119139-23-0 cas 119139-23-0 Carbonyl Compounds
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Bisindolylmaleimide IV (BIM IV) is an inhibitor of pyruvate phosphate dikinase (PPDK). It is a cell-permeable potent and somewhat selective inhibitor of PKC with IC50 of 87 nM. BIM IV is a cell-permeable inhibitor of protein kinase C (PKC) with IC50 values reported to range from 0.10 to 0.55 µM. It also inhibits protein kinase A (PKA) with an IC50 of 2.7 μM. #
Details:
Bisindolylmaleimide IV (BIM IV) is an inhibitor of pyruvate phosphate dikinase (PPDK). It is a cell-permeable potent and somewhat selective inhibitor of PKC with IC50 of 87 nM. BIM IV is a cell-permeable inhibitor of protein kinase C (PKC) with IC50 values reported to range from 0.10 to 0.55 µM. It also inhibits protein kinase A (PKA) with an IC50 of 2.7 μM. #
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