CasNo.9054-89-1,Recombinant human copper, zinc-superoxide dismutase (rh-Cu, Zn-SOD),(9054-89-1) Suppliers

1 Kilogram	FOB Price:USD 25.0000 -350.0000

Min.Order :1 Kilogram
Purity: 99% up
Payment Terms : L/C,D/A,D/P,T/T,

Keywords

Recombinant human copper zinc-superoxide dismutase rh-Cu, Zn-SOD

Quick Details

Appearance:White powder
Application:1. There is a significant effect of sunscreen, light skin darkening is mainly due to oxygen free radical damage, Superoxide Dismutase can effectively prevent skin by ionizing radiation (especially UV)
PackAge:1kg/bag ;5kg/drum:25KG/drum
ProductionCapacity:20|Metric Ton|Month
Storage:in low tempreture
Transportation:in low tempreture

Superiority:

Why is SINOWAY:

1) Specialized in pharmaceutical and healthcare industrial for 34 years.

2) ISO 9001:2015 & SGS audited supplier .

3) Accept various payment terms : T.T 30-60 days.

4) We have warehouse in USA with quickly shipment .

5) We can do different terms of FOB ,CIF/CIP ,DDP ...

Product technology information

Product Name: Superoxide Dismutase

Cas No.: 9054-89-1

EINECS: 232-943-0

Appearance: White or light blue crystalline powder

Enzyme activity: 1000U/mg-6000U/mg

PH: 6.5~7.6

Protein content: 99%

Details:

Product Information

Product Name	Recombinant human copper, zinc-superoxide dismutase (rh-Cu, Zn-SOD)
Resource	Escherichia coli (E. coli)
CAS NO.	9054-89-1
Mol. Wt.	17 kDa
Purity	95% up by SDS-PAGE analysis
Appearance	White/light blue powder or floccule
Activity	5000-10000IU/mg,25000IU/mg
Grade	Cosmetic grade

Usage

Superoxide dismutase (SOD) is a category of metalloenzyme, extensively existing in all living organisms (e.g. animals, plants, microorganisms, etc.). Based on its metallicity, SOD is categorized into copper, zinc-SOD (Cu, Zn-SOD), manganese-SOD (Mn-SOD) and iron-SOD (Fe-SOD). SOD has a physiological significance that can convert toxic superoxide free radicals into hydrogen peroxide, it’s the primary substance to scavenge oxygen free radicals in living organisms. It has been demonstrated that there are up to 60 diseases directly related to oxygen free radicals and SOD level has been known as an illustrated indicator for aging and death. SOD can prohibit superoxide free radicals-induced damage at cellular level and locally repair damaged cells. It plays more and more important role in anti-oxidation in living organisms. SOD is one of components in cosmetic products, approved by Ministry of Health of the People's Republic of China, because it can delay aging, regulate immune response and blood lipid level, and prevent radiation.

Function of Cu, Zn-SOD(SOD1):

1. Cu, Zn-SOD(SOD1) binds copper and zinc ions and is one of three superoxide dismutases responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic and mitochondrial intermembrane space protein, acting as a homodimer to convert naturally occurring, but harmful, superoxide radicals to molecular oxygen and hydrogen peroxide.Hydrogen peroxide can then be broken down by another enzyme called catalase.

2. Cu, Zn-SOD (SOD1) has been postulated to localize to the outer mitochondrial membrane (OMM), where superoxide anions would be generated, or the intermembrane space. The exact mechanisms for its localization remains unknown, but its aggregation to the OMM has been attributed to its association with BCL-2. Wildtype SOD1 has demonstrated antiapoptotic properties in neural cultures, while mutant SOD1 has been observed to promote apoptosis in spinal cord mitochondria, but not in liver mitochondria, though it is equally expressed in both. Two models suggest SOD1 inhibits apoptosis by interacting with BCL-2proteins or the mitochondria itself.

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