for sale 282526-98-1 282526-98-1 trader with best price Cetilistat

Min.Order / FOB Price:Get Latest Price

100 Gram	FOB Price: USD 10.0000

100 Gram

FOB Price: USD 10.0000

Min.Order :100 Gram
Purity: 99%min
Payment Terms : T/T,

Keywords

for sale 282526-98-1 282526-98-1 trader with best price Cetilistat

Quick Details

Appearance:White crystalline powder
Application:Cetilistat
PackAge:10g/pack ,100g/pack,1kg/pack (aluminum foil bag)
ProductionCapacity:10000|Kilogram|Year
Storage:Storage in a dry, ventilated place under normal temperature
Transportation:by EMS,FEDEX,DHL

Superiority:

for sale 282526-98-1 282526-98-1 trader with best price Cetilistat

Cetilistat is an inhibitor of pancreatic lipase (IC₅₀s = 5.95 and 54.8 nM for the human and rat enzymes, respectively). It reduces increases in plasma triglyceride levels in an oral fat tolerance test, indicating decreased intestinal fat absorption, in rats when administered at a doses ranging from 3 to 100 mg/kg. Dietary administration of cetilistat (4.9-50.7 mg/kg per day) decreases body weight gain without affecting food intake, as well as reduces increases in plasma triglyceride and leptin levels in a rat model of high-fat diet-induced obesity. It also reduces viral load in the culture supernatant of Vero E6 cells infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; EC₉₀ = 2.9 µM) and inhibits SARS-CoV-2 replication in a plaque reduction assay (EC₅₀ = 1.13 µM).

Cetilistat is a novel inhibitor of pancreatic lipase being developed by Alizyme for the treatment of obesity and associated co-morbidities, including type 2 diabetes.

Details:

Catalogue Number	C280800
Chemical Name	Cetilistat
Synonyms	2-(Hexadecyloxy)-6-methyl-4H-3,1-benzoxazin-4-one; ATL 962;
CAS Number	282526-98-1
Molecular Formula	C??H??NO?
Appearance	White to Off-White Solid
Melting Point	74-76°C
Molecular Weight	401.58
Storage	Refrigerator
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
Category	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
Applications	A novel pancreatic lipase inhibitor for the treatment of obesity in both diabetic and non-diabetic patients.