2-Amino-4-methoxypyridine

Details:

2-Amino-4-methoxypyridine Chemical Properties
Melting point     120-121°C
Boiling point     258.6±20.0 °C(Predicted)
density     1.139±0.06 g/cm3(Predicted)
storage temp.     Keep in dark place,Inert atmosphere,Room temperature
pka    7.79±0.11(Predicted)
form     Solid
color     Pale yellow
Water Solubility     Soluble in Dimethyl sulfoxide, methanol. Slightly soluble in water.
λmax    280nm(CHCl3)(lit.)
Sensitive     Air Sensitive
InChIKey    QPHBCOSULYSASF-UHFFFAOYSA-N
CAS DataBase Reference    10201-73-7(CAS DataBase Reference)
Safety Information
Hazard Codes     Xi,Xn
Risk Statements     22-36/37/38
Safety Statements     36/37/39
WGK Germany     3
HazardClass     6.1
HazardClass     IRRITANT
MSDS Information
2-Amino-4-methoxypyridine Usage And Synthesis
Chemical Properties    Pale Yellow Solid
Uses    2-Amino-4-methoxypyridine is a highly selective inducible nitric oxide synthase inhibitors.
Synthesis Reference(s)    The Journal of Organic Chemistry, 72, p. 4554, 2007 DOI: 10.1021/jo070189y
2-Amino-4-methoxypyridine Preparation Products And Raw materials
Raw materials    Methanol-->Sodium-->2-Amino-4-chloropyridine-->(4-METHOXY-PYRIDIN-2-YL)-CARBAMIC ACID TERT-BUTYL ESTER-->4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID AMIDE-->4-Methoxypyridine N-oxide-->2-Bromo-4-methoxypyridine-->4-METHOXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER-->2-Picolinic acid-->Sodium methanolate
Preparation Products    [1,2,4]Triazolo[1,5-a]pyridin-7-ol