Factory supply Omeprazole 99% CAS119141-89-8

Details:

English name: omeprazole
CAS number: 119141-89-8
Molecular formula: C17H19N3O3S
Molecular weight: 345.41600
Exact mass: 345.11500
PSA: 96.31000
LogP: 3.76540
Appearance and properties: white or off-white crystalline powder; odorless; easy to change color when exposed to light. Easily soluble in dichloromethane, slightly soluble in methanol or ethanol, slightly soluble in acetone, insoluble in water; soluble in 0.1mol/L sodium hydroxide solution.
Density: 1.37 g/cm1
Boiling point: 600ºC at 760 mmHg
Flash point: 316.7ºC
Storage conditions: 2-8ºC

Omeprazole, mainly used for duodenal ulcer and Zollinger-Ellison syndrome, can also be used for gastric ulcer and reflux esophagitis; intravenous injection can be used for the treatment of acute bleeding of peptic ulcer. Combined with amoxicillin and clindamycin or with metronidazole and clarithromycin to kill Helicobacter pylori.

pharmacology
               It is a proton pump inhibitor and is a lipid-soluble weakly basic drug. It is easy to concentrate in an acidic environment and specifically acts on the secretory microtubules formed by the apical membrane of gastric mucosal parietal cells and tubular vesicles in the cytoplasm, that is, where the proton pump (H+, K+-ATPase) of gastric parietal cells is located. It is converted into the active form of sulfenamide, and irreversibly combined with the sulfhydryl group of the proton pump through disulfide bonds, thereby inhibiting the activity of H+, K+-ATPase, blocking the last step of gastric acid secretion, and making H+ in parietal cells. Can not be transported into the stomach cavity, so that the acid content of gastric juice is greatly reduced. It has a strong inhibitory effect on basal gastric acid and stimulation-induced gastric acid secretion.

Applicable symptoms
Erectile dysfunction and pulmonary hypertension.

Dosage
The recommended dose of this product is 10mg, which is taken before sexual activity and is not affected by food. If the effect of taking 10mg is not significant, you can take 20mg, at least 30 minutes before sex.
The maximum frequency of dosing is once a day.

Quality:

1. order products, before delivery, according to customer needs, we will provide such as coa, msds, nuclear magnetic resonance (nmr), chiral product spinning, or customer specified demand quality indicators.
2. can be given sample and technical confirmation.
3. professional packaging, or packaging and transportation according to the needs of customers.

Service:
1. track the product freight service all the way.
2. to cooperate with the customs clearance.
3. optimize the production process according to the customer's needs.
4. joint research and development of products according to customer needs.