99% up by HPLC 6-Benzofurancarboxylic Acid 77095-51-3

99% up by HPLC 6-Benzofurancarboxylic Acid 77095-51-3

Min.Order / FOB Price:Get Latest Price

1 Kilogram	Negotiable

1 Kilogram

Negotiable

Min.Order :1 Kilogram
Purity: 99.9%
Payment Terms : L/C,D/A,D/P,T/T

Keywords

6-Benzofurancarboxylic Acid lifitegrast intermediate 77095-51-3

Quick Details

Appearance:White or almost white hygroscopic powder
Application:API
PackAge:25kg per drum
ProductionCapacity:1000|Kilogram|Month
Storage:Normal temperature
Transportation:normal temperature.

Superiority:

Why is SINOWAY:

1) Specialized in pharmaceutical and healthcare industrial for 34 years.

2) ISO 9001:2015 & SGS audited supplier .

3) Accept various payment terms : T.T 30-60 days.

4) We have warehouse in USA with quickly shipment .

5) We can do different terms of FOB ,CIF/CIP ,DDP ...

Details:

Product name	6-Benzofurancarboxylic acid
Systematic name	1-benzofuran-6-carboxylic acid; Benzofuran-6-carboxylic acid; LIFI-009; Lifitegrast intermediate
CAS No.	77095-51-3
Molecular Formula	C9H6O3
Molecular Weight	162.145
Quality Standard	99% up
Appearance	White powder

6-Benzofurancarboxylic acid is one of the key intermediates of Lifitegrast.

Function of Lifitegrast

Lifitegrast is a leukocyte function antigen 1 antagonist used in the treatment of dry eye. Lifitegras can bind to leukocyte functional antigen 1 (LFA-1), preventing the binding of LFA-1 to its cognate ligand intercellular adhesion molecule-1 (ICAM-1). ICAM-1 is overexpressed in the corneal Chemicalbook membrane and conjunctival tissues of patients with dry eye, and LFA-1 binds to ICAM-1 to promote the formation of immune synapses, leading to activation of T cells and migration to target tissues. In vitro studies have shown that Lifitegrast can inhibit T cell adhesion to ICAM-1 and also inhibit the secretion of inflammatory cytokines in human peripheral blood mononuclear cells.