112887-68-0 Raltitrexed C21H22N4O6S
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Raltitrexed Basic information |
Product Name: | Raltitrexed |
Synonyms: | RALTITREXED;(s)-2-[(1-{5-[methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-thiophen-2-yl}-methanoyl)-amino]-pentanedioic acid;ICI-D-1694;N-[[5-[[(1,4-Dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]-L-glutamic Acid;Tomudex;ZD-1694;L-Glutamic acid, N-[[5-[[(3,4-dihydro-2-methyl-4-oxo-6-quinazolinyl)methyl]methylamino]-2-thienyl]carbonyl]-;(S)-2-[(1-{5-[Methyl-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-amino]-thiophen-2-yl}-methanoyl)-amino]-pentanedioic acid |
CAS: | 112887-68-0 |
MF: | C21H22N4O6S |
MW: | 458.49 |
EINECS: | |
Product Categories: | Active Pharmaceutical Ingredients;Raltitrexed;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitors |
Mol File: | 112887-68-0.mol |
Raltitrexed Chemical Properties |
mp | 176-1800C |
storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
CAS DataBase Reference | 112887-68-0(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi,T |
Risk Statements | 36/38-25-61 |
Safety Statements | 26-37/39-45-53 |
Raltitrexed Usage And Synthesis |
Chemical Properties | Yellow Crystalline Powder |
Usage | Folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic |
Raltitrexed Preparation Products And Raw materials |
Raw materials | N-Bromosuccinimide-->DIETHYL GLUTAMATE |
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