Add time:09/28/2019 Source:infona.pl
A novel and efficient approach for the straightforward synthesis of biologically significant acenaphtho[1,2-b]quinoline derivatives in good yields utilizing CuI as a catalyst with a broad array of substrates has been developed. The strategy features as a CuI-catalyzed cascade reaction involving the formation of two new CC bonds and one new CN bond with high atom economy. A proposed mechanism for the reaction is described.
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