1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:120511-73-1
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inquiryAs the leading manufactory of base chemicals in China market,it has developed organicetc chemical,inorganic chemical,paint chemical and detergent chemical etc..With many years develop and operation experience,facts proof that the equipments,which
Cas:120511-73-1
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inquiryHotsale Anastrozole/ Anti Estrogen Steroids Anastrozole 99% CAS120511-73-1 Items Standard Results Description Off White crystalline powder Complies Solubil
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inquiryUSD12/g.We have manufactured this product for 9 years. Hangzhou Hysen pharma CO.,LTD. is a professional Pharmaceutical company. We are specialized in manufacturing and R&D of API & Intermediates, Contract Manufacturing, Contract Research,
Cas:120511-73-1
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inquiry1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products wi
Cas:120511-73-1
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inquirySpecification: In-house, USP; Certification: GMP; ISO 9001; EIR (by US FDA) Appearance:White Storage: Preserve in well-closed containers. Store at room temperature. Application:It is used to treat breast cancer in women after menopause (change o
Items Standard Result Appearance White or off-white crystalline powder Confirm Solubility Fr
Cas:120511-73-1
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inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
Cas:120511-73-1
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inquiry1.High quality : the purity is 99% min . through multiple producing procedures. 2.Competitive price : low price because of our skilled production technolpgy ,save the production cost at most , and give big profit room to our customers
Cas:120511-73-1
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inquiryAnastrozole CAS No.:120511-73-1 Name: Anastrozole Synonyms: Tetramethyl-5-(1H-1,2,4-triazol-1ylmethyl) 1,3-benzenediacetionitrile Molecular Structure Molecular Formula: C17H19N5
Cas:120511-73-1
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Type:Other
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:120511-73-1
Min.Order:1 Kilogram
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Name:anastrozole CAS no:120511-73-1 Grade:Medical, scientific research and export Molecular formula:C17H19N5 Molecular weight:293.37 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data
Cas:120511-73-1
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inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Anastrozole Basic information Product Name: Anastrozole Synonyms: ICI-D-1033;ARIMIDEX;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE;ANASTRAZOLE;ANASTROZOLE;tetramethyl-5-(1h-
Cas:120511-73-1
Min.Order:1 Gram
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Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:120511-73-1
Min.Order:1 Kilogram
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Type:Trading Company
inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after the dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available &diam
Cas:120511-73-1
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Type:Trading Company
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod
Cas:120511-73-1
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inquiryAnastrozole Testing Method: HPLC Appearance: White crystalline powder Introduction: The drug is appropriately used when using substantial amounts of aromatizing , or when one is prone to gynecomastia . Arimidex does not have the side effects
Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s
Cas:120511-73-1
Min.Order:10 Gram
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Type:Other
inquiryAppearance:White powder Storage:room temperature Package:25kg/drum Application:chemicals Transportation:Express/Sea/Air Port:any port in china
Cas:120511-73-1
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Lab/Research institutions
inquiry1.Prompt Goods; 2.Flexible payment terms; 3.Documents & Certificate support. Name: Anastrozole Molecular Structure: Formula: C17H19N5 Molecular Weight : 293.37 Synonyms: ICI-D-1033;ARIMIDEX;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4
Cas:120511-73-1
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquirysupplier 120511-73-1 good producer 120511-73-1 Hot Sale Anastrozole Anastrozole, chemically known as 2,2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropiononitrile) a derivative of benzotriazole with the CAS registry number 120511-73
Cas:120511-73-1
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryAnastrozole CAS:120511-73-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate
Cas:120511-73-1
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryWe have overseas warehouses in California, Nuevo Laredo, Mexico, Vancouver, Canada, Amsterdam, The Netherlands and Melbourne, Australia. Overseas warehouses can provide some of the best selling products. We look forward to cooperating with strong loc
Cas:120511-73-1
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryHebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several
Cas:120511-73-1
Min.Order:25 Gram
FOB Price: $90.0 / 100.0
Type:Trading Company
inquiryAPI name: Anastrozole Certificates: GMP, DMF CAS No.: 120511-73-1 Chemical name: ICI-D-1033;ARIMIDEX;1-[3,5-DI-(1-METHYL-1-CYANO)-ETHYL]-BENZYL-1,2,4-TRIAZOLE;α,α,α’,α'-Tetramethyl-5-(1H-1,2,4-triazol-1
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:120511-73-1
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryShanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many ye
Cas:120511-73-1
Min.Order:5 Kilogram
FOB Price: $7.8
Type:Lab/Research institutions
inquiry1,2,4-Triazole
2-[3-bromomethyl-5-(cyanodimethylmethyl)phenyl]-2-methylpropanenitrile
anastrozol
Conditions | Yield |
---|---|
With potassium tert-butylate In toluene at 9 - 21℃; for 4.5h; | 100% |
With tetrabutylammomium bromide; potassium hydroxide In water; toluene at 75 - 80℃; for 2h; Solvent; Temperature; Reagent/catalyst; | 82% |
With tetrabutylammomium bromide; potassium carbonate; potassium hydroxide In toluene at 85 - 90℃; for 5h; | 47% |
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride In tetrahydrofuran at 45 - 55℃; for 7h; Reagent/catalyst; Solvent; | 90% |
anastrozol
Conditions | Yield |
---|---|
With sodium azide; sulfuric acid; copper(II) sulfate In methanol; water for 1h; Solvent; Reflux; | 82% |
With hydrogenchloride; sodium nitrite In water at 0 - 20℃; for 9 - 9.5h; | 81.24% |
Stage #1: 4-amino-1-[3,5-bis(1-cyano-1-methylethyl)benzyl]-4H-1,2,4-triazolium bromide With hydrogenchloride; sodium nitrite In water at -5 - 20℃; for 8h; Stage #2: With urea In water Stage #3: With ammonia In water; toluene at 0 - 25℃; for 4h; |
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]-di(2-methylpropionitrile) hydrobromide
anastrozol
Conditions | Yield |
---|---|
With sodium carbonate In water Product distribution / selectivity; | 74.7% |
Conditions | Yield |
---|---|
In ethanol for 2h; Heating / reflux; | 72.49% |
anastrozole mesylate
anastrozol
Conditions | Yield |
---|---|
With ammonia In methanol; water at 18 - 22℃; Product distribution / selectivity; | 71.5% |
anastrozol
Conditions | Yield |
---|---|
With sodium carbonate In water Product distribution / selectivity; | 69.5% |
With sodium hydrogencarbonate In water Product distribution / selectivity; | |
In water for 48.5h; Product distribution / selectivity; |
α,α,α',α'-tetramethyl-5-chloromethyl-1,3-benzene diacetonitrile
sodium triazole
anastrozol
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 18h; | 52% |
In DMF (N,N-dimethyl-formamide) at 20℃; for 18h; |
2-[3-bromomethyl-5-(cyanodimethylmethyl)phenyl]-2-methylpropanenitrile
sodium triazole
anastrozol
Conditions | Yield |
---|---|
Stage #1: 2-[3-bromomethyl-5-(cyanodimethylmethyl)phenyl]-2-methylpropanenitrile; sodium triazole In N,N-dimethyl-formamide at 45 - 50℃; for 4h; Stage #2: With hydrogenchloride; water at 50℃; pH=2; Stage #3: With ammonia In water at 0 - 5℃; pH=8 - 9; | 34% |
In N,N-dimethyl-formamide at 20℃; for 1h; | 34% |
In N,N-dimethyl-formamide at 20℃; for 1h; | 34% |
B
2-[3-(1-carbamoyl-1-methylethyl)-5-[1,2,4]triazol-1-ylmethylphenyl]-isobutyramide
C
anastrozol
Conditions | Yield |
---|---|
Stage #1: 4-amino-1-[3,5-bis(1-cyano-1-methylethyl)benzyl]-4H-1,2,4-triazolium bromide With hydrogenchloride; sodium nitrite In water at -5 - 20℃; Stage #2: With ammonia; water at 0 - 25℃; for 4h; | A 0.36% B 0.05% C n/a |
α,α,α',α'-tetramethyl-5-chloromethyl-1,3-benzene diacetonitrile
anastrozol
Conditions | Yield |
---|---|
Stage #1: 1,2,4-Triazole With sodium methylate In methanol at 20 - 30℃; for 0.25h; Stage #2: α,α,α',α'-tetramethyl-5-chloromethyl-1,3-benzene diacetonitrile In N,N-dimethyl acetamide at 15 - 55℃; for 3h; Product distribution / selectivity; |
anastrozol
Conditions | Yield |
---|---|
With ammonia In water; toluene for 0.5h; pH=8.5 - 9.0; Product distribution / selectivity; | |
With ammonia In water; ethyl acetate for 0.5h; pH=8.5 - 9.0; Product distribution / selectivity; | |
With ammonia In water at 10 - 20℃; for 0.75h; pH=~ 9.00 - 10.00; Product distribution / selectivity; |
anastrozol
Conditions | Yield |
---|---|
With ammonia In water Product distribution / selectivity; |
anastrozol
Conditions | Yield |
---|---|
With ammonia In water Product distribution / selectivity; |
A
α,α,α',α'-tetramethyl-5-(4H-1,2,4-triazol-4ylmethyl)-1,3-benzene-diacetonitrile
B
anastrozol
Conditions | Yield |
---|---|
With sodium carbonate In water; ethyl acetate for 0.333333h; Product distribution / selectivity; | |
With sodium carbonate In water; ethyl acetate; toluene for 0.25h; Product distribution / selectivity; |
2-[3-bromomethyl-5-(cyanodimethylmethyl)phenyl]-2-methylpropanenitrile
anastrozol
Conditions | Yield |
---|---|
Stage #1: 1,2,4-Triazole With sodium hydroxide In 1-methyl-pyrrolidin-2-one at 20 - 60℃; for 14 - 55h; Stage #2: 2-[3-bromomethyl-5-(cyanodimethylmethyl)phenyl]-2-methylpropanenitrile In 1-methyl-pyrrolidin-2-one at -26 - -20℃; for 18 - 26h; Stage #3: With acetic acid In 1-methyl-pyrrolidin-2-one pH=6.5 - 7; Product distribution / selectivity; |
Conditions | Yield |
---|---|
With N-Bromosuccinimide; dibenzoyl peroxide In N-methyl-acetamide; tetrachloromethane; water | |
Stage #1: 3,5-bis(2-cyanoprop-2-yl)toluene; sodium triazole In N,N-dimethyl-formamide at 45 - 50℃; for 4h; Stage #2: With hydrogenchloride In water at 50℃; pH=1 - 2; Stage #3: With ammonia In water at 0 - 5℃; pH=8 - 9; |
1,2,4-Triazole
α,α,α',α'-tetramethyl-5-chloromethyl-1,3-benzene diacetonitrile
A
α,α,α',α'-tetramethyl-5-(4H-1,2,4-triazol-4ylmethyl)-1,3-benzene-diacetonitrile
B
anastrozol
Conditions | Yield |
---|---|
In acetonitrile |
anastrozol
sodium triazole
A
α,α,α',α'-tetramethyl-5-(4H-1,2,4-triazol-4ylmethyl)-1,3-benzene-diacetonitrile
B
anastrozol
Conditions | Yield |
---|---|
In isopropyl alcohol Product distribution / selectivity; Heating / reflux; | |
In N,N-dimethyl-formamide at 5 - 35℃; for 0.5 - 4h; Product distribution / selectivity; | |
In n-heptane Product distribution / selectivity; Heating / reflux; | |
In acetone Product distribution / selectivity; Heating / reflux; | |
In methanol Product distribution / selectivity; Heating / reflux; |
2-[3-bromomethyl-5-(cyanodimethylmethyl)phenyl]-2-methylpropanenitrile
sodium triazole
A
3,5-bis(2-cyanoprop-2-yl)toluene
B
α,α,α',α'-tetramethyl-5-(4H-1,2,4-triazol-4ylmethyl)-1,3-benzene-diacetonitrile
C
anastrozol
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at -10 - -5℃; for 0.75h; Product distribution / selectivity; |
2-[3-(cyano-dimethyl-methyl)-5-hydroxymethyl-phenyl]-2-methyl-propionitrile
1-(4-toluenesulfonyl)-1H-1,2,4-triazole
anastrozol
Conditions | Yield |
---|---|
Stage #1: 2-[3-(cyano-dimethyl-methyl)-5-hydroxymethyl-phenyl]-2-methyl-propionitrile With sodium hydride In tetrahydrofuran at 70℃; for 0.5h; Stage #2: 1-(4-toluenesulfonyl)-1H-1,2,4-triazole In ISOPROPYLAMIDE at 20℃; for 0.333333h; Product distribution / selectivity; | |
Stage #1: 2-[3-(cyano-dimethyl-methyl)-5-hydroxymethyl-phenyl]-2-methyl-propionitrile With sodium hydride In 1,4-dioxane at 70 - 85℃; for 0.5 - 0.583333h; Stage #2: 1-(4-toluenesulfonyl)-1H-1,2,4-triazole In 1,4-dioxane at 10 - 125℃; for 3.33333 - 5h; Product distribution / selectivity; | |
Stage #1: 2-[3-(cyano-dimethyl-methyl)-5-hydroxymethyl-phenyl]-2-methyl-propionitrile With sodium hydride In 1,2-dimethoxyethane at 70℃; for 0.5h; Stage #2: 1-(4-toluenesulfonyl)-1H-1,2,4-triazole In 1,2-dimethoxyethane at 10 - 100℃; for 3.33333h; Product distribution / selectivity; | |
Stage #1: 2-[3-(cyano-dimethyl-methyl)-5-hydroxymethyl-phenyl]-2-methyl-propionitrile With sodium hydride In tetrahydrofuran at 70℃; for 0.5h; Stage #2: 1-(4-toluenesulfonyl)-1H-1,2,4-triazole In tetrahydrofuran at 10 - 100℃; for 3.33333h; Product distribution / selectivity; |
1,2,4-Triazole
2-[3-bromomethyl-5-(cyanodimethylmethyl)phenyl]-2-methylpropanenitrile
A
α,α,α',α'-tetramethyl-5-(4H-1,2,4-triazol-4ylmethyl)-1,3-benzene-diacetonitrile
B
anastrozol
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide for 2h; Product distribution / selectivity; Reflux; | |
With potassium carbonate In toluene at 9 - 21℃; for 4.5h; Overall yield = 71.8 %; Overall yield = 42.14 g; |
3,5-bis(2-cyanoprop-2-yl)toluene
anastrozol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione / 2,2'-azobis(isobutyronitrile) / cyclohexane / 4 h / 25 - 85 °C 2.1: isopropyl alcohol / 5 h / 80 - 85 °C 3.1: hydrogenchloride; sodium nitrite / water / 8 h / -5 - 20 °C 3.2: 4 h / 5 - 25 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: N-Bromosuccinimide; acetic acid; 2,2'-azobis(isobutyronitrile) / acetonitrile / 6.5 h / 65 °C / Reflux; Industrial scale 2.1: 3 h / Reflux; Industrial scale 3.1: hydrogenchloride; sodium nitrite / acetonitrile; water / 4 h / 15 - 22 °C / Industrial scale 3.2: 0.5 h / 20 °C / Industrial scale 3.3: 12 h / 12 °C / Industrial scale View Scheme |
dichloro(benzene)ruthenium(II) dimer
ammonium tetrafluroborate
anastrozol
Conditions | Yield |
---|---|
In ethanol for 6h; Reflux; Inert atmosphere; | 68% |
dichloro(benzene)ruthenium(II) dimer
sodium tetraphenyl borate
anastrozol
Conditions | Yield |
---|---|
In ethanol for 6h; Reflux; Inert atmosphere; | 60% |
Conditions | Yield |
---|---|
In water at 40℃; for 24h; | 58% |
Sodium trans-Bis(dimethhyl sulfoxide) tetrachlororuthenate(III)
anastrozol
Conditions | Yield |
---|---|
In acetone Inert atmosphere; Schlenk technique; | 56% |
Conditions | Yield |
---|---|
In ethanol for 24h; Inert atmosphere; Reflux; | 52% |
anastrozol
A
3,5-bis(2-cyanoprop-2-yl)toluene
Conditions | Yield |
---|---|
With tetraethylammonium perchlorate; triethylamine In dimethyl sulfoxide at 20℃; for 9h; Electrolysis; Green chemistry; | A 47% B 26% |
silver tetrafluoroborate
chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium (II)
anastrozol
Conditions | Yield |
---|---|
In acetone for 2h; Inert atmosphere; Schlenk technique; Reflux; | 36% |
anastrozol
Conditions | Yield |
---|---|
In acetonitrile at 80℃; under 775.743 Torr; for 48h; Microwave irradiation; Inert atmosphere; Schlenk technique; | 22% |
Conditions | Yield |
---|---|
In ethyl acetate Product distribution / selectivity; Acidic conditions; |
toluene-4-sulfonic acid
anastrozol
Conditions | Yield |
---|---|
In acetone at 20 - 25℃; for 13h; | |
In acetone for 1h; | |
In toluene for 0.5h; Heating / reflux; |
anastrozol
Conditions | Yield |
---|---|
With hydrogenchloride In isopropyl alcohol; acetone | |
With hydrogenchloride In water at 20 - 42℃; for 0.5h; Product distribution / selectivity; |
(2E)-but-2-enedioic acid
anastrozol
Conditions | Yield |
---|---|
In acetone at 20℃; for 5h; Heating / reflux; |
oxalic acid
anastrozol
Conditions | Yield |
---|---|
In isopropyl alcohol at 20℃; for 4h; |
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