1000340-51-1 Usage
General Description
7-Methyl-1H-indazole-3-carbaldehyde is a chemical compound belonging to the class of indazoles. It is an aldehyde derivative containing a methyl substitution at the 7th position of the indazole ring. 7-Methyl-1H-indazole-3-carbaldehyde is commonly used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals. Its structure and reactivity make it an important intermediate in organic synthesis, and it is known for its potential biological activities. The compound is often utilized in drug discovery and development, as well as in research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1000340-51-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,0,3,4 and 0 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1000340-51:
(9*1)+(8*0)+(7*0)+(6*0)+(5*3)+(4*4)+(3*0)+(2*5)+(1*1)=51
51 % 10 = 1
So 1000340-51-1 is a valid CAS Registry Number.
1000340-51-1Relevant articles and documents
An optimized procedure for direct access to 1: H -indazole-3-carboxaldehyde derivatives by nitrosation of indoles
Chevalier, Arnaud,Ouahrouch, Abdelaaziz,Arnaud, Alexandre,Gallavardin, Thibault,Franck, Xavier
, p. 13121 - 13128 (2018)
Indazole derivatives are currently drawing more and more attention in medicinal chemistry as kinase inhibitors. 1H-indazole-3-carboxaldehydes are key intermediates to access to a variety of polyfunctionalized 3-substituted indazoles. We report here a general access to this motif, based on the nitrosation of indoles in a slightly acidic environment. These very mild conditions allow the conversion of both electron-rich and electron-deficient indoles into 1H-indazole-3-carboxaldehydes.
