1000353-40-1

Basic information

• Product Name: N-cyclohexyl-N-[5-methyl-2-(4-nitrophenyl)imidazo[1,2-a]pyridine-3-yl]amine
• Synonyms: N-cyclohexyl-N-[5-methyl-2-(4-nitrophenyl)imidazo[1,2-a]pyridine-3-yl]amine
• CAS NO: 1000353-40-1
• Molecular Weight: 350.42
• Mol File: 1000353-40-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-cyclohexyl-N-[5-methyl-2-(4-nitrophenyl)imidazo[1,2-a]pyridine-3-yl]amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-cyclohexyl-N-[5-methyl-2-(4-nitrophenyl)imidazo[1,2-a]pyridine-3-yl]amine(1000353-40-1)
• EPA Substance Registry System: N-cyclohexyl-N-[5-methyl-2-(4-nitrophenyl)imidazo[1,2-a]pyridine-3-yl]amine(1000353-40-1)

Safety Data

• Hazardous Substances Data: 1000353-40-1(Hazardous Substances Data)

Upstream product

• 1824-81-3 2-Amino-6-methylpyridine 
• 931-53-3 Cyclohexyl isocyanide 
• 555-16-8 4-nitrobenzaldehdye 

Relevant articles and documents

Nanomagnetically modified sulfuric acid (γ-Fe2O3@SiO2-OSO3H): An efficient, fast, and reusable green catalyst for the Ugi-like Groebke-Blackburn-Bienaymé three-component reaction under solvent-free conditions

Superparamagnetic nanoparticles of modified sulfuric acid (γ-Fe2O3@SiO2-OSO3H) represent a straightforward and green catalyst for the rapid synthesis of aminoimidazopyridine skeletons via the Ugi-like Groebke-Blackburn-Bienaymé three-component reaction. The γ-Fe2O3@SiO2-OSO3H catalyst could be recovered and reused in five reaction cycles, giving a total TON = 453. The products were prepared under solvent-free conditions without any additives.

Choline chloride/urea as a deep eutectic solvent/organocatalyst promoted three-component synthesis of 3-aminoimidazo-fused heterocycles via Groebke-Blackburn-Bienayme process

The catalytic activity of urea-, metal- and organic acid-based/choline chloride deep eutectic solvents/organocatalysts was investigated for the synthesis of 3-aminoimidazo-fused heterocycles via a one-pot domino reaction of an aldehyde, an isocyanide and 2-aminoheterocycles. The urea-based/choline chloride system exhibited significant catalytic activity for the reaction and could be reused in four consecutive reactions with no considerable loss in catalytic activity.

RuCl3-catalyzed solvent-free Ugi-type Groebke-Blackburn synthesis of aminoimidazole heterocycles

RuCl3 catalyzes the efficient Ugi-type Groebke-Blackburn condensations of aldehydes and 2-amino pyridines with isocyanides under solvent free conditions without any ligand or activator. It is shown that RuCl 3 catalyzed aminoimidazol