100062-14-4

Basic information

• Product Name: N-(2-chloropyridin-3-yl)-4-methylbenzenesulfonamide
• Synonyms: N-(2-chloropyridin-3-yl)-4-methylbenzenesulfonamide
• CAS NO: 100062-14-4
• Molecular Weight: 282.751
• Mol File: 100062-14-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-chloropyridin-3-yl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chloropyridin-3-yl)-4-methylbenzenesulfonamide(100062-14-4)
• EPA Substance Registry System: N-(2-chloropyridin-3-yl)-4-methylbenzenesulfonamide(100062-14-4)

Safety Data

• Hazardous Substances Data: 100062-14-4(Hazardous Substances Data)

Upstream product

• 6298-19-7 2-chloro-3-aminopyridine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 106320-35-8 N-(2-chloro-[3]pyridyl)-N-methyl-toluene-4-sulfonamide 
• 40932-43-2 (2-chloro-pyridin-3-yl)-methyl-amine 

Relevant articles and documents

One-Pot Synthesis of Substituted Benzo[b]furans and Indoles from Dichlorophenols/Dichloroanilines Using a Palladium-Dihydroxyterphenylphosphine Catalyst

Disubstituted benzo[b]furans were synthesized by ortho-selective Sonogashira coupling of dichlorophenols and terminal alkynes, followed by cyclization and Suzuki-Miyaura coupling in one pot, using a palladium-dihydroxyterphenylphosphine (Cy-DHTP) catalyst. The use of substoichiometric amounts of tetrabutylammonium chloride was effective in accelerating the Suzuki-Miyaura coupling. This protocol was also successfully applied to the one-pot synthesis of disubstituted indoles from dichloroaniline derivatives.