100074-46-2

Basic information

• Product Name: 2(5H)-Furanone, 3-(4-fluorophenyl)-4-hydroxy-
• CAS NO: 100074-46-2
• Molecular Formula: C10H7FO3
• Molecular Weight: 194.162
• Mol File: 100074-46-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 3-(4-fluorophenyl)-4-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 3-(4-fluorophenyl)-4-hydroxy-(100074-46-2)
• EPA Substance Registry System: 2(5H)-Furanone, 3-(4-fluorophenyl)-4-hydroxy-(100074-46-2)

Safety Data

• Hazardous Substances Data: 100074-46-2(Hazardous Substances Data)

Usage

Derivative of furanone

Yes

Heterocyclic organic compound

Yes

Hydroxy group present

Yes

Fluorophenyl substituent attached

Yes

Potential pharmaceutical and medicinal properties

Yes, including as an antimicrobial agent

Importance in organic chemistry

Yes

Potential applications in various industries

Yes

Upstream product

• 96-35-5 glycolic acid methyl ester 
• 34837-84-8 4-fluorobenzeneacetic acid methyl ester 
• 405-50-5 p-Fluorophenylacetic acid 
• 100074-33-7 phenylacetic acid 

Downstream Products

• 1504595-03-2 C₁₂H₁₀BrFO₃ 
• 1514777-20-8 7-(4-(2-(3-(4-fluorophenyl)furan-2(5H)-one-4-yloxy)ethyl)piperazin-1-yl)-1-(4-fluorophenyl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 1514777-18-4 7-(4-(2-(3-(4-fluorophenyl)furan-2(5H)-one-4-yloxy)ethyl)piperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 1421237-22-0 C₂₂H₁₉F₂NO₄ 
• 1421237-25-3 C₂₂H₁₉F₂NO₄ 
• 1421237-07-1 C₂₂H₂₁F₂NO₅ 
• 1283094-23-4 4-(3,5-dibromophenylamino)-3-(4-fluorophenyl)furan-2(5H)-one 
• 100074-72-4 5-Bromo-3-(4-fluoro-phenyl)-4-methoxy-5H-furan-2-one 
• 100074-59-7 3-(4-fluorophenyl)-4-methoxy-5H-furan-2-one 

Relevant articles and documents

Compound, as well as preparation method and application thereof

The application discloses a compound of which the structure is represented as the following formula, wherein R1 is selected from any one of F, Cl, Br, C1-C5 alkyl group, and a group having the structure as the formula (1), n = 0, 1, 2, 3, 4 or 5; the R2 is selected from any one of a group having the structure as the formula (1), a group having the structure as the formula (2), and a group having the structure as the formula (3). The compound has simple preparation method, can be used as a neuraminidase inhibitor, and has excellent antivirus activity.

Synthesis, molecular docking and biological evaluation of 3-arylfuran-2(5H)-ones as anti-gastric ulcer agent

3-Arylfuran-2(5H)-one derivatives show good antibacterial activity and were determined as tyrosyl-tRNA synthetase (TyrRS) inhibitors. In a systematic medicinal chemistry exploration, we demonstrated chemical opportunities to treat infections caused by Hel

A facile synthesis, antibacterial activity of pulvinone and its derivatives

Pulvinone and several 3-fluoro-4-morpholino substituted pulvinone derivatives were synthesized in five steps from a common precursor, phenyl acetic acid. Most of synthetic morpholine substituted pulvinones showed inhibitory activity against Esherichia col