1001129-69-6

Basic information

• Product Name: (7S)-(+)-3-(4-methoxyphenyl)acrylic acid 8,8-dimethyl-2-oxo-6,7-dihydro-2H,8H-pyrano[3,2-g]chromen-7-yl ester
• Synonyms: (7S)-(+)-3-(4-methoxyphenyl)acrylic acid 8,8-dimethyl-2-oxo-6,7-dihydro-2H,8H-pyrano[3,2-g]chromen-7-yl ester
• CAS NO: 1001129-69-6
• Molecular Weight: 406.435
• Mol File: 1001129-69-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (7S)-(+)-3-(4-methoxyphenyl)acrylic acid 8,8-dimethyl-2-oxo-6,7-dihydro-2H,8H-pyrano[3,2-g]chromen-7-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (7S)-(+)-3-(4-methoxyphenyl)acrylic acid 8,8-dimethyl-2-oxo-6,7-dihydro-2H,8H-pyrano[3,2-g]chromen-7-yl ester(1001129-69-6)
• EPA Substance Registry System: (7S)-(+)-3-(4-methoxyphenyl)acrylic acid 8,8-dimethyl-2-oxo-6,7-dihydro-2H,8H-pyrano[3,2-g]chromen-7-yl ester(1001129-69-6)

Safety Data

• Hazardous Substances Data: 1001129-69-6(Hazardous Substances Data)

Upstream product

• 5993-18-0 decursinol 
• 830-09-1 3-(4'-methoxyphenyl)propenoic acid 
• 42996-84-9 p-methoxycinnamoyl chloride 

Downstream Products

• 1001129-70-9 (7S)-(+)-3-(4-hydroxyphenyl)acrylic acid 8,8-dimethyl-2-oxo-6,7-dihydro-2H,8H-pyrano[3,2-g]chromen-7-yl ester 
• 1262418-80-3 (7S)-(+)-3-(4-acetoxyphenyl)acrylic acid 8,8-dimethyl-2-oxo-6,7-dihydro-2H,8H-pyrano[3,2-g]chromen-7-yl ester 

Relevant articles and documents

Synthesis and evaluation of (+)-decursin derivatives as inhibitors of the Wnt/β-catenin pathway

We synthesized (+)-decursin derivatives substituted with cinnamoyl- and phenyl propionyl groups originating from (+)-CGK062 and screened them using a cell-based assay to detect relative luciferase reporter activity. Of this series, compound 8b, in which a

COMPOSITION COMPRISING DECURSIN DERIVATIVE FOR TREATING AND PREVENTING ATOPIC DERMATITIS

The present invention relates to the novel decursin derivatives, the preparation thereof and the composition comprising the same. The novel decursin derivatives of the present invention showedpotent inhibiting activity of the release of MCP-1, IL-6 and IL-8 induced by dermite in THP-1 or EoL-1 cell, therefore the compounds can be useful in treating or preventing atopic dermatitis.