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1001201-61-1

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1001201-61-1 Usage

General Description

Tert-butyl 4-((5R,7S)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxylate is a chemical compound that is used in medicinal chemistry research as a potential drug candidate. It is a piperazine derivative with a cyclopenta[d]pyrimidine moiety, and its tert-butyl ester group provides stability and enhances its pharmacokinetic properties. The compound has shown potential for therapeutic applications in the treatment of various diseases, particularly in the modulation of biological pathways associated with the targeted receptor. Further research and development efforts are underway to explore its pharmacological properties and evaluate its potential for clinical use.

Check Digit Verification of cas no

The CAS Registry Mumber 1001201-61-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,1,2,0 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1001201-61:
(9*1)+(8*0)+(7*0)+(6*1)+(5*2)+(4*0)+(3*1)+(2*6)+(1*1)=41
41 % 10 = 1
So 1001201-61-1 is a valid CAS Registry Number.

1001201-61-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 4-[(5R,7S)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazine-1-carboxylate

1.2 Other means of identification

Product number -
Other names tert-Butyl 4-((5R,7S)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1001201-61-1 SDS

1001201-61-1Relevant articles and documents

Asymmetric Synthesis of Akt Kinase Inhibitor Ipatasertib

Han, Chong,Savage, Scott,Al-Sayah, Mohammad,Yajima, Herbert,Remarchuk, Travis,Reents, Reinhard,Wirz, Beat,Iding, Hans,Bachmann, Stephan,Fantasia, Serena M.,Scalone, Michelangelo,Hell, André,Hidber, Pirmin,Gosselin, Francis

, p. 4806 - 4809 (2017/09/23)

A highly efficient asymmetric synthesis of the Akt kinase inhibitor ipatasertib (1) is reported. The bicyclic pyrimidine 2 starting material was prepared via a nitrilase biocatalytic resolution, halogen-metal exchange/anionic cyclization, and a highly dia

Synthesis of Akt inhibitor ipatasertib. part 2. Total synthesis and first kilogram scale-up

Remarchuk, Travis,St-Jean, Frederic,Carrera, Diane,Savage, Scott,Yajima, Herbert,Wong, Brian,Babu, Srinivasan,Deese, Alan,Stults, Jeffrey,Dong, Michael W.,Askin, David,Lane, Jonathan W.,Spencer, Keith L.

, p. 1652 - 1666 (2015/02/19)

Herein, the first-generation process to manufacture Akt inhibitor Ipatasertib through a late-stage convergent coupling of two challenging chiral components on multikilogram scale is described. The first of the two key components is a trans-substituted cyc

COMBINATIONS OF AKT INHIBITOR COMPOUNDS AND VEMURAFENIB, AND METHODS OF USE

-

, (2012/10/18)

The invention provides a combination of a) a compound of Formula Ia: [insert Formula Ia], or a pharmaceutically acceptable salt thereof, and b) vemurafenib or a pharmaceutically acceptable salt thereof for the prophylactic or therapeutic treatment of a hy

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