1001273-08-0Relevant articles and documents
Synthesis of 3′,3′-difluoro-2′-hydroxymethyl-4′, 5′-unsaturated carbocyclic nucleosides
Yang, Yan-Yan,Xu, Jun,You, Zheng-Wei,Xu, Xiu-Hua,Qiu, Xiao-Long,Qing, Feng-Ling
, p. 5437 - 5440 (2008/09/18)
3′,3′-Difluoro-2′-hydroxymethyl-4′, 5′-unsaturated carbocyclic nucleosides 1-3 have been stereoselectively synthesized from ester 10, which can be conveniently prepared from 2,3-isopropylidene-D-glyceraldehyde 7 in five steps. The whole synthesis highligh