100160-69-8 Usage
General Description
(1S,2S)-2-Amino-2,3-dihydro-1H-inden-1-ol hydrochloride is a chemical compound with the molecular formula C9H11NO.HCl. It is a chiral compound, meaning it has two enantiomeric forms, (1S,2S) and (1R,2R). This chemical is an amino alcohol, which means it contains both an amine and an alcohol functional group. It is commonly used in the synthesis of pharmaceuticals and as a chiral auxiliary in asymmetric synthesis. Its hydrochloride form makes it more water-soluble and stable, making it a useful compound for various chemical reactions and biological applications. (1S,2S)-2-Amino-2,3-dihydro-1H-inden-1-ol hydrochloride is important in the field of organic chemistry and drug development due to its chiral nature and versatile reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 100160-69-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,1,6 and 0 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 100160-69:
(8*1)+(7*0)+(6*0)+(5*1)+(4*6)+(3*0)+(2*6)+(1*9)=58
58 % 10 = 8
So 100160-69-8 is a valid CAS Registry Number.
100160-69-8Relevant articles and documents
Efficient diastereoselective synthesis of cis-2-amino-1-indanol derivatives and cis- and trans-1-amino-2-indanol via Pd-catalyzed hydrogenation
Nguyen, Thi Ha,Ma, Eunsook
supporting information, p. 3717 - 3728 (2021/11/01)
(±)-cis-2-amino-1-indanol was diastereoselectively synthesized from 1,2-indanedion-2-oxime in ethanol at 25 °C under 10% Pd/C-catalyzed hydrogenation conditions. Under the same hydrogenation condition, 1,2-indanedion-2-oxime and their derivatives having one and/or two electron-donating groups in aliphatic or aromatic part of indanyl ring were diastereoselectively reduced to racemic cis-2-amino-1-indanol derivatives. From 1,2-indanedion-1-oxime, (±)-trans-1-amino-2-indanol was obtained in ethanol at 25 °C over a 10% Pd/BaSO4 catalyst. In contrast, the 10% Pd/BaSO4-catalyzed hydrogenation reaction in ethanol at 45 °C afforded cis-1-hydroxyamino-2-indanol from 1,2-indanedion-1-oxime, followed by reduction to form (±)-cis-1-amino-2-indanol. The diastereoselectivity of β-aminoindanols was dependent on the Pd catalyst, reaction temperature, and pH of the reaction medium.
