100223-10-7

Basic information

• Product Name: Phenylalanine, N-acetyl-2-methyl-, methyl ester
• CAS NO: 100223-10-7
• Molecular Formula: C13H17NO3
• Molecular Weight: 235.283
• Mol File: 100223-10-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phenylalanine, N-acetyl-2-methyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phenylalanine, N-acetyl-2-methyl-, methyl ester(100223-10-7)
• EPA Substance Registry System: Phenylalanine, N-acetyl-2-methyl-, methyl ester(100223-10-7)

Safety Data

• Hazardous Substances Data: 100223-10-7(Hazardous Substances Data)

Upstream product

• 529-20-4 2-methylphenyl aldehyde 
• 192319-66-7 4-(2-methylphenyl)methylene-2-methyl-5(4H)-oxazolone 
• 1030359-40-0 C₁₃H₁₅NO₃ 
• 35356-70-8 Methyl 2-acetamidoacrylate 
• 33872-80-9 o-tolyl magnesium chloride 
• 889863-27-8 methyl (Z)-2-acetamido-3-(2'-methylphenyl)-2-propenoate 
• 95-46-5 2-methylphenyl bromide 

Relevant articles and documents

SYNTHESIS OF α-AMINO ACID DERIVATIVES BY COPPER(I)-CATALYZED CONJUGATE ADDITION OF GRIGNARD REAGENTS TO METHYL 2-ACETAMIDOACRYLATE

The reactions of Grignard reagent with methyl 2-acetamidoacrylate in the presence of CuI give fair to good yields of α-amino esters; the corresponding α-deutero- or α-methyl-derivatives are obtained upon quenching with D+ or CH3I, respectively.

Chiral bisphosphine ligands based on quinoline oligoamide foldamers: application in asymmetric hydrogenation

A series of chiral bisphosphine ligands were designed and synthesized based on single-handed quinoline oligoamide foldamers. The bisphosphine ligands can coordinate with Rh(cod)2BF4 in a 1 : 1 stoichiometry and the resulted chiral Rh(i) catalysts were applied in the asymmetric hydrogenation of α-dehydroamino acid esters, in which excellent conversions and promising levels of enantioselectivity were achieved.