100236-26-8

Basic information

• Product Name: 2H-Isoindole-2-acetic acid, a-[[(2-aminophenyl)thio]methyl]-1,3-dihydro-1,3-dioxo-, (R)-
• CAS NO: 100236-26-8
• Molecular Formula: C17H14N2O4S
• Molecular Weight: 342.375
• Mol File: 100236-26-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2H-Isoindole-2-acetic acid, a-[[(2-aminophenyl)thio]methyl]-1,3-dihydro-1,3-dioxo-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Isoindole-2-acetic acid, a-[[(2-aminophenyl)thio]methyl]-1,3-dihydro-1,3-dioxo-, (R)-(100236-26-8)
• EPA Substance Registry System: 2H-Isoindole-2-acetic acid, a-[[(2-aminophenyl)thio]methyl]-1,3-dihydro-1,3-dioxo-, (R)-(100236-26-8)

Safety Data

• Hazardous Substances Data: 100236-26-8(Hazardous Substances Data)

Upstream product

• 95779-63-8 (R)-3-(2-nitrophenyl)thio-2-phthalimidopropionic acid 
• 22509-74-6 N-ethoxycarbonylphthalimide 
• 60115-45-9 S-(o-nitrophenyl)-L-cysteine 
• 88-74-4 2-nitro-aniline 

Downstream Products

• 7028-57-1 2-methyl-3,4-dihydro-3-oxo-2H-1,4-benzothiazine 
• 95779-48-9 tert-butyl 3(R)-[1(S)-ethoxycarbonyl-3-phenylpropyl]amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-acetate 
• 95779-47-8 tert-butyl 3(R)-[1(R)-ethoxycarbonyl-3-phenylpropyl]amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-acetate 
• 95779-49-0 tert-butyl 3(R)-[1(S)-ethoxycarbonyl-3-cyclohexylpropyl]amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-acetate 
• 95779-50-3 (R)-2-((R)-5-tert-Butoxycarbonylmethyl-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylamino)-4-cyclohexyl-butyric acid ethyl ester 
• 103604-00-8 tert-butyl (R)-3-<(S)-1-ethoxycarbonyl-3-cyclohexylpropyl>amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-α-methylacetate 
• 103604-00-8 tert-butyl (R)-3-<(R)-1-ethoxycarbonyl-3-cyclohexylpropyl>amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-α-methylacetate 
• 94590-60-0 3(R)-amino>-5-(carboxymethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one hydrochloride 
• 94590-62-2 3(R)-amino>-5-(carboxymethyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one hydrochloride 
• 103584-46-9 (S)-2-[(R)-5-(1-Carboxy-ethyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylamino]-4-cyclohexyl-butyric acid ethyl ester; hydrochloride 
• 103584-46-9 (R)-2-[(R)-5-(1-Carboxy-ethyl)-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylamino]-4-cyclohexyl-butyric acid ethyl ester; hydrochloride 
• 95779-55-8 3(R)-[1(S)-ethoxycarbonyl-3-cyclohexylpropyl]amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzothiazepine-5-acetic acid hydrochloride 
• 95779-56-9 (R)-2-((R)-5-Carboxymethyl-4-oxo-2,3,4,5-tetrahydro-benzo[b][1,4]thiazepin-3-ylamino)-4-cyclohexyl-butyric acid ethyl ester; hydrochloride 
• 95779-61-6 C₂₁H₂₀N₂O₅S^(2-)*2Na⁽¹⁺⁾ 

Relevant articles and documents

BENZAZEPINE-, BENZOXAZEPINE- AND BENZOTHIAZEPINE-N-ACETIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Compounds with neutral endopeptidase (NEP) inhibitory activity corresponding to the formula I STR1 in which R 1 is a lower alkoxy-lower-alkyl group whose lower alkoxy radical is substituted by a lower alkoxy group, or a phenyl-lower-alkyl or phenyloxy-lower-alkyl group which can optionally be substituted in the phenyl ring by lower alkyl, lower alkoxy or halogen, or a naphthyl-lower-alkyl group, A is CH 2, O or S,R 2 is hydrogen or halogen,R. sup.3 is hydrogen or halogen,R 4 is hydrogen or a group forming a biolabile ester, andR 5 is hydrogen or a group forming a biolabile ester, and the physiologically acceptable acid addition salts thereof.

Condensed, seven-membered ring compounds, their production and use

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Synthesis and angiotensin converting enzyme inhibitory activity of 1,5-benzothiazepine and 1,5-benzoxazepine derivatives. I

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