1002727-49-2

Basic information

• Product Name: 3-Bromo-5-(hydroxy-phenyl-methyl)-pyridin-4-one
• CAS NO: 1002727-49-2
• Molecular Weight: 280.121
• Mol File: 1002727-49-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-Bromo-5-(hydroxy-phenyl-methyl)-pyridin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-5-(hydroxy-phenyl-methyl)-pyridin-4-one(1002727-49-2)
• EPA Substance Registry System: 3-Bromo-5-(hydroxy-phenyl-methyl)-pyridin-4-one(1002727-49-2)

Safety Data

• Hazardous Substances Data: 1002727-49-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 25813-25-6 3,5-dibromo-4-hydroxypyridine 

Downstream Products

• 1002727-50-5 3-benzyl-5-bromopyridin-4-one 

Relevant articles and documents

Pyridinone diketo acids: inhibitors of HIV replication

A new class of diketo acids constructed on pyridinone scaffolds, designed as inhibitors of HIV replication through inhibition of HIV integrase, is described. These compounds are useful in the prevention or treatment of infection by HIV and in the treatment of AIDS and ARC, either as the compounds, or as pharmaceutically acceptable salts, with pharmaceutically acceptable carriers, used alone or in combination with antivirals, immunomodulators, antibiotics, vaccines, and other therapeutic agents, especially other anti-HIV compounds (including other integrase-based anti-HIV agents). Methods of treating AIDS and ARC and methods of treating or preventing infection by HIV are also described.

Monocyclic heterocycles as kinase inhibitors

The present invention is directed to compounds having the formula and methods for using them for the treatment of cancer.