1003-86-7Relevant articles and documents
CHIRAL ACETYLENES AS SYNTHETIC INTERMEDIATES. V. A REINVESTIGATION ON THE SYNTHESIS OF OPTICALLY ACTIVE ISOXAZOLES
Falorni, Massimo,Lardicci, Luciano,Giacomelli, Giampaolo
, p. 7 - 10 (2007/10/02)
The synthesis of 3- or 5-alkyl isoxazoles and pyrazoles has been achieved starting from alkyl-substituted acetylenic ketones: the influence of the structure of the carbonyl compound on the isomeric composition of the heterocyclic compound has been studied.Some optically active monoalkyl-substituted isoxazoles have also been prepared: in this context, an investigation on the stereochemistry of the cyclization process has been carried out.