100370-35-2

Basic information

• Product Name: N-(1,5-dihydroxypentan-2-yl)benzamide
• Synonyms: N-(1,5-dihydroxypentan-2-yl)benzamide
• CAS NO: 100370-35-2
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.26828
• Mol File: 100370-35-2.mol
• Article Data: 3

Chemical Properties

• Appearance: white
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-(1,5-dihydroxypentan-2-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1,5-dihydroxypentan-2-yl)benzamide(100370-35-2)
• EPA Substance Registry System: N-(1,5-dihydroxypentan-2-yl)benzamide(100370-35-2)

Safety Data

• Hazardous Substances Data: 100370-35-2(Hazardous Substances Data)

Usage

General Description

N-(1,5-dihydroxypentan-2-yl)benzamide is a chemical compound with the molecular formula C14H19NO3. It is a benzamide derivative that contains a five-carbon chain with two hydroxyl groups attached to the second carbon. N-(1,5-dihydroxypentan-2-yl)benzamide is often used in research and pharmaceutical development due to its potential biological activities. It may have applications in medicine, including in the treatment of certain diseases or conditions. Further research is needed to fully understand the potential uses and effects of N-(1,5-dihydroxypentan-2-yl)benzamide.

Upstream product

• 6094-36-6 N-benzoyl-L-glutamic acid 
• 86555-46-6 dimethyl (2S)-2-benzoylaminopentanedioate 
• 124126-80-3 N-benzoyl-L-glutamic acid α-methyl ester 

Relevant articles and documents

Toward the development of chemoprevention agents. Part 1: Design, synthesis, and anti-inflammatory activities of a new class of 2,5-disubstituted-dioxacycloalkanes

A new class of 2,5-disubstituted-dioxacycloalkanes were designed and synthesized via stereoselective synthetic method as cancer chemoprevention agents. The anti-inflammatory activities of these compounds were tested using the xylene-induced mouse ear edema model. Some of these compounds exhibited comparable or better anti-inflammatory activities than that of aspirin suggesting that they can be further developed as potential anti-inflammatory drug lead compounds. In addition, treatment of these anti-inflammatory agents did not prolong tail bleeding time in mice. The structure/activity relationships were also analyzed among these compounds.

Stereoselective transacetalization of 1,1,3,3-tetramethoxypropane and N- benzoylaminodiols

The transacetalization of 1,1,3,3-tetramethoxypropane and an N- benzoylaminodiol provided stereoselectively the corresponding 2,5- disubstituted-1,3-dioxanes. The stereochemistry of the rings formed in the transacetalization depended on the structure of the amino diol, and the ratio of the products depended on the reaction conditions, as expected. This kind of stereoselective transacetalization not only gives a series of useful building blocks but also generates interesting 1,3-dioxanes which target protein kinase C.