100393-27-9Relevant articles and documents
Regiodivergent Copper Catalyzed Borocyanation of 1,3-Dienes
Jia, Tao,He, Qiong,Ruscoe, Rebecca E.,Pulis, Alexander P.,Procter, David J.
, p. 11305 - 11309 (2018)
Copper catalyzed multi-functionalization of unsaturated carbon-carbon bonds is a powerful tool for the generation of complex molecules. We report a regiodivergent process that allows a switch between 1,4-borocupration and 4,1-borocupration of 1,3-dienes upon a simple change in ligand. The subsequently generated allyl coppers are trapped in an electrophilic cyanation to selectively generate densely functionalized and synthetically versatile 1,2- or 4,3-borocyanation products.