100414-89-9Relevant articles and documents
Total synthesis of verticillene. A biomimetic approach to the taxane family of alkaloids
Begley, Michael J.,Jackson, Christopher B.,Pattenden, Gerald
, p. 4907 - 4924 (1990)
Intramolecular reductive coupling of the bis-aldehyde (10) in the presence of Ti(O), followed by 1,4-reducdon of the resulting tetraene (9) using sodium in ammonia, provides a facile synthesis of E,E-verticillene (8), the putative biogenetic precursor of
A Unique Skeletal Rearrangement of a Bicyclo[33.1]nonanetrione to a Tetrahydroquinolin-2(1 H)-one System
Shen, Qi,Liu, Fang,Zhang, Yu-Chao,Wang, Jie,Zhang, Lei,Wang, Yue,Xu, Hong-Xi,Shao, Zhuzhou,Cao, Yang,Wu, Jing,Liang, Yong,Li, Jian-Xin
, p. 1711 - 1716 (2018/07/06)
The unexpected formation of a 4-hydroxytetrahydroquinolin-2(1 H)-one from a bicyclo[3.3.1]nonanetrione system and an amino alcohol in the presence of TsOH is reported. The mechanism of this transformation was studied by DFT calculations. The reaction provides an entry to the synthesis of highly functionalized 4-hydroxytetrahydroquinolin-2(1 H)-ones.