100422-04-6

Basic information

• Product Name: (2,2,2-trifluoroethyl)-λ³-iodanediyl bis(2,2,2-trifluoroacetate)
• Synonyms: (2,2,2-trifluoroethyl)-λ³-iodanediyl bis(2,2,2-trifluoroacetate)
• CAS NO: 100422-04-6
• Molecular Weight: 435.97
• Mol File: 100422-04-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2,2,2-trifluoroethyl)-λ³-iodanediyl bis(2,2,2-trifluoroacetate)(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2,2-trifluoroethyl)-λ³-iodanediyl bis(2,2,2-trifluoroacetate)(100422-04-6)
• EPA Substance Registry System: (2,2,2-trifluoroethyl)-λ³-iodanediyl bis(2,2,2-trifluoroacetate)(100422-04-6)

Safety Data

• Hazardous Substances Data: 100422-04-6(Hazardous Substances Data)

Upstream product

• 353-83-3 1,1,1-trifluoro-2-iodoethane 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 408510-42-9 (2,2,2-trifluoroethyl)phenyliodonium triflate 
• 100422-07-9 2,2,2-trifluoroethyl(phenyl)iodonium trifluoromethanesulfonate 
• 307501-98-0 (1,1,1-trifluoroethyl) phenyl iodonium (N,N'-bis-trifluoromethylsulfonyl) imide 
• 166903-46-4 1-[hydroxy(tosyloxy)iodo]-1H,1H-perfluoroethane 

Relevant articles and documents

Syntheses and lipophilicity measurement of Nα/N-terminus-1,1-dihydroperfluoroalkylated α-amino acids and small peptides

(1,1-Dihydroperfluoroalkyl)phenyliodonium N,N-bis(trifluoromethylsulfonyl)imides (4, n = 0-2) were synthesized and used to transfer the corresponding 1,1-dihydroperfluoroalkyl groups to the α-amino group of (l)tyrosine. The obtained Nα-2,2,2-trifluoroethylated (l)tyrosine (6, n = 0) was further used as the N-terminus in the solid phase peptide synthesis of leucine enkephalin analogue. The lipophilicity of the Nα-1,1-dihydroperfluoroalkylated (l)tyrosines (6, n = 0-2) and N-terminus-2,2,2-trifluoroethylated leucine enkephalin analogue (7), as well as the corresponding parent compounds, was measured.