10043-45-5

Basic information

• Product Name: 1,3,4,6-tetra-O-acetyl-2-deoxy-2-{[(4-nitrophenyl)sulfonyl]amino}hexopyranose
• CAS NO: 10043-45-5
• Molecular Formula: C₂₀H₂₄N₂O₁₃S
• Molecular Weight: 532.4752
• Mol File: 10043-45-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 645.9°C at 760 mmHg
• Flash Point: 344.4°C
• Density: 1.48g/cm³
• Vapor Pressure: 1.43E-16mmHg at 25°C
• Refractive Index: 1.566
• CAS DataBase Reference: 1,3,4,6-tetra-O-acetyl-2-deoxy-2-{[(4-nitrophenyl)sulfonyl]amino}hexopyranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4,6-tetra-O-acetyl-2-deoxy-2-{[(4-nitrophenyl)sulfonyl]amino}hexopyranose(10043-45-5)
• EPA Substance Registry System: 1,3,4,6-tetra-O-acetyl-2-deoxy-2-{[(4-nitrophenyl)sulfonyl]amino}hexopyranose(10043-45-5)

Safety Data

• Hazardous Substances Data: 10043-45-5(Hazardous Substances Data)

Usage

General Description

1,3,4,6-tetra-O-acetyl-2-deoxy-2-{[(4-nitrophenyl)sulfonyl]amino}hexopyranose is a synthetic chemical compound with a complex structure. It is a derivative of hexopyranose, a type of sugar, and contains multiple acetyl groups and a sulfonamide moiety. The presence of the nitrophenyl group makes it a potential photoaffinity label for studying carbohydrate-protein interactions. 1,3,4,6-tetra-O-acetyl-2-deoxy-2-{[(4-nitrophenyl)sulfonyl]amino}hexopyranose has been used in research applications such as probing the binding sites of glycosidases and glycosyltransferases, as well as in the development of carbohydrate-based therapeutic agents. Its chemical properties and potential applications make it a valuable tool for studying and manipulating carbohydrate biochemistry.

Upstream product

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Relevant articles and documents

HF-Induced Intramolecular C-Arylation and C-Alkylation/Fluorination of 2-Aminoglycopyranoses

Internal C-aryl and C-alkyl glycosides derived from 2-aminoglycopyranoses have been synthesized, exploiting a HF-mediated stereoselective intramolecular glycosylation. These conditions are compatible with acetate protecting groups and allow introduction of aromatics with various electronic distributions at the anomeric position. This strategy also provides straightforward entry to original fluorinated sugar-azacycle hybrids via a tandem internal C-glycosylation/fluorination reaction starting from 2-N-allyl/propargyl glycopyranoses. All cyclizations proceed in a 1,2-cis stereocontrolled manner.