100449-39-6

Basic information

• Product Name: Tetrahydro-N-methyl-N-phenyl-2-thioxo-2H-1,3-thiazin-3-thiocarboxamid
• CAS NO: 100449-39-6
• Molecular Weight: 282.455
• Mol File: 100449-39-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Tetrahydro-N-methyl-N-phenyl-2-thioxo-2H-1,3-thiazin-3-thiocarboxamid(CAS DataBase Reference)
• NIST Chemistry Reference: Tetrahydro-N-methyl-N-phenyl-2-thioxo-2H-1,3-thiazin-3-thiocarboxamid(100449-39-6)
• EPA Substance Registry System: Tetrahydro-N-methyl-N-phenyl-2-thioxo-2H-1,3-thiazin-3-thiocarboxamid(100449-39-6)

Safety Data

• Hazardous Substances Data: 100449-39-6(Hazardous Substances Data)

Upstream product

• 5554-48-3 Tetrahydro-1,3-thiazin-2-thion 
• 19009-45-1 N-methyl-N-phenylthiocarbamoyl chloride 

Relevant articles and documents

Investigations on 1,3 Thiazines, 35. - Oxidations of Thiocarbamidates, 9. - Unusual Rearrangement Upon Thiocarbamoylation of Tetrahydro-2H-1,3-thiazin-2-one

During thiocarbamoylation of tetrahydro-2H-1,3-thiazin-2-one (4) with N,N-disubstituted thiocarbamoyl chlorides the 3-carboxamides 2 were isolated besides the expected 3-thiocarboxamides 6.The carboxamides 2 are interpreted as products of initial O-thiocarbamoylation, subsequent Newman-Kwart rearrangement, and final S->N-transcarbamoylation.Structures were ensured by independent syntheses and 13C-NMR spectroscopy.Thiocarbamidate and thiourea substructures were converted into the corresponding oxygen analogues by oxidative desulfurisation.