100465-53-0

Basic information

• Product Name: methyl 4-(1'-hydroxycyclohexanyl)-3-morpholinocrotonate
• Synonyms: methyl 4-(1'-hydroxycyclohexanyl)-3-morpholinocrotonate
• CAS NO: 100465-53-0
• Molecular Weight: 283.368
• Mol File: 100465-53-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-(1'-hydroxycyclohexanyl)-3-morpholinocrotonate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(1'-hydroxycyclohexanyl)-3-morpholinocrotonate(100465-53-0)
• EPA Substance Registry System: methyl 4-(1'-hydroxycyclohexanyl)-3-morpholinocrotonate(100465-53-0)

Safety Data

• Hazardous Substances Data: 100465-53-0(Hazardous Substances Data)

Upstream product

• 55261-56-8 3-morpholino-but-2-enoic acid methyl ester 
• 101471-73-2 methyl ester of trans-β-(morpholino)acrylic acid 
• 108-94-1 cyclohexanone 
• 83577-48-4 methyl 4-trimethylsilyl-3-morpholinocrotonate 

Relevant articles and documents

Chemistry of 4-trimethylsilyl-3-dialkylaminocrotonate esters and the cycloaromatization reactions with enamines

Methyl 4-trimethylsilyl-3-dialkylaminocrotonate is synthesized by the silylation of methyl 3-dialkylaminocrotonate.It reacts with carbonyl electrophiles at its γ-position.The unusual regiochemistry of this reaction is studied and rationalized.It reacts with enamines derived from acyclic ketones to give aromatic compounds in a 3C+3C combination and with enamines derived from cycloketones of 5- to 8-membered rings to give aromatic compounds in a 4C+2C combination.A mechanism for this cycloaromatization reaction is proposed.