100485-52-7

Basic information

• Product Name: 1-(naphthyl-⁽²⁾)-ethanone-⁽¹⁾-seqtrans-oxime
• Synonyms: 1-(naphthyl-⁽²⁾)-ethanone-⁽¹⁾-seqtrans-oxime
• CAS NO: 100485-52-7
• Molecular Weight: 185.225
• Mol File: 100485-52-7.mol
• Article Data: 62

Chemical Properties

• CAS DataBase Reference: 1-(naphthyl-⁽²⁾)-ethanone-⁽¹⁾-seqtrans-oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(naphthyl-⁽²⁾)-ethanone-⁽¹⁾-seqtrans-oxime(100485-52-7)
• EPA Substance Registry System: 1-(naphthyl-⁽²⁾)-ethanone-⁽¹⁾-seqtrans-oxime(100485-52-7)

Safety Data

• Hazardous Substances Data: 100485-52-7(Hazardous Substances Data)

Upstream product

• 110-86-1 pyridine 
• 64-17-5 ethanol 
• 93-08-3 methyl 2-naphthyl ketone 
• 123-91-1 1,4-dioxane 
• 7647-01-0 hydrogenchloride 
• 7732-18-5 water 
• 827-54-3 2-naphthylethylene 
• 79-24-3 Nitroethane 
• 91-20-3 naphthalene 

Downstream Products

• 1201-74-7 1-(2-Naphthyl)ethylamine 
• 93-08-3 methyl 2-naphthyl ketone 
• 942066-02-6 N-[(E)-1-(2-naphthyl)ethylidene]diphenylphosphinic amide 
• 3557-63-9 2,6-bis(naphthalen-2-yl)-4-phenylpyridine 
• 106651-19-8 (S)-N-(2-naphthalen-2-yl-ethyl)-P,P-diphenylphosphinamide 
• 177750-24-2 N-(1-(naphthalen-2-yl)vinyl)acetamide 
• 581-97-5 2-acetylaminonaphthalene 

Relevant articles and documents

A Three-Step Procedure for Asymmetric Catalytic Reductive Amidation of Ketones

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Expedient one-pot synthesis of pyrroles from ketones, hydroxylamine, and 1,2-dichloroethane

2- and 2,3-Substituted pyrroles are readily synthesized in a one-pot procedure from ketones, hydroxylamine hydrochloride, and 1,2-dichloroethane in the KOH/DMSO system (120 °C, 2-4 h), the yields of pyrroles ranging 11-85%. Aliphatic, cycloaliphatic, aromatic, and heteroaromatic ketones tolerate the reaction conditions.

Rhodium-Catalyzed C?H Activation/Annulation Cascade of Aryl Oximes and Propargyl Alcohols to Isoquinoline N-Oxides

A β-hydroxy elimination instead of common oxidization to carbonyl group in secondary propargyl alcohols was successfully developed to form 2-benzyl substituted isoquinoline N-oxides by a Rhodium-catalyzed C?H activation and annulation cascade, in which moderate to excellent yields (up to 92%) could be obtained under mild reaction conditions, along with good regioselectivity, broad generality and applicability. (Figure presented.).

Synthesis, Structure, and Photochemical Behavior of [5]Heli-viologen Isomers

The syntheses of isomeric helical viologens that have potential applications in supramolecular chemistry and catalysis have been developed. The structures of the molecules and their solid-state packing motifs have been determined by X-ray crystallography. Computational studies demonstrate that the magnitude of their racemization barriers is primarily determined by the identity of the helical scaffold and is insensitive to the placement of the viologen functional group. The isomers are similar in their photophysical behavior but very different in their photochemical behavior.

Nitrimines as reagents for metal-free formal C(sp2)-C(sp2) cross-coupling reactions

Nitrimines are employed as powerful reagents for metal-free formal C(sp2)-C(sp2) cross-coupling reactions. The new chemical process is tolerant of a wide array of nitrimine and heterocyclic coupling partners giving rise to the corresponding di- or trisubstituted alkenes, typically in high yield and with high stereoselectivity. This method is ideal for the metal-free construction of heterocycle-containing drug targets, such as phenprocoumon.

Polysubstituted Indole Synthesis via Palladium/Norbornene Cooperative Catalysis of Oxime Esters

Polysubstituted indoles are prevalent in pharmaceuticals, agrochemicals, and organic materials. Presented herein is the fact that polyfunctionalized indoles can be efficiently constructed from easily accessible oxime esters and aryl iodides, involving a palladium/norbornene synergistic synthesis. The reaction is enabled by a unique class of electrophiles in palladium/norbornene cooperative catalysis, which are oxime esters derived from simple ketone. The broad substrate scope and high functional group tolerance could make this method attractive for the synthesis of polysubstituted indoles.

Rhodium(iii)-catalyzed asymmetric [4+1] spiroannulations of: O -pivaloyl oximes with α-diazo compounds

Chiral RhIII catalysts can catalyze the asymmetric [4+1] spiroannulation of O-pivaloyl oximes with α-diazo homophthalimides under redox-neutral and acid/base-neutral conditions, leading to formation of chiral spirocyclic imines as a result of C-H activation and N-O cleavage. The reaction proceeded with high efficiency and features broad substrate scope, mild reaction conditions, and high to excellent enantioselectivities. This journal is