10049-90-8

Basic information

• Product Name: N,N-diethyl-α-hydroxy-α-phenylbenzeneacetamide
• Synonyms: N,N-diethyl-α-hydroxy-α-phenylbenzeneacetamide
• CAS NO: 10049-90-8
• Molecular Weight: 283.37
• Mol File: 10049-90-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N,N-diethyl-α-hydroxy-α-phenylbenzeneacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethyl-α-hydroxy-α-phenylbenzeneacetamide(10049-90-8)
• EPA Substance Registry System: N,N-diethyl-α-hydroxy-α-phenylbenzeneacetamide(10049-90-8)

Safety Data

• Hazardous Substances Data: 10049-90-8(Hazardous Substances Data)

Upstream product

• 119-61-9 benzophenone 
• 128721-75-5 Te-butyl N,N-dimethylcarbamotelluroate 
• 7647-01-0 hydrogenchloride 
• 412018-06-5 diethylamino-diphenyl-acetic acid diethylamide 
• 617-84-5 N-formyldiethylamine 
• 3004-58-8 N,N-diethyl-2,2-diphenylacetamide 
• 5411-58-5 ethyl N,N-diethyloxamate 
• 109-89-7 diethylamine 

Downstream Products

• 3004-58-8 N,N-diethyl-2,2-diphenylacetamide 
• 113135-23-2 diethyl-(2-hydroxy-2,2-diphenyl-ethyl)-methyl-ammonium; iodide 
• 76-93-7 Benzilic acid 
• 109-89-7 diethylamine 

Relevant articles and documents

Barbier Continuous Flow Preparation and Reactions of Carbamoyllithiums for Nucleophilic Amidation

An ambient temperature continuous flow method for nucleophilic amidation and thioamidation is described. Deprotonation of formamides by lithium diisopropylamine (LDA) affords carbamoyllithium intermediates that are quenched in situ with various electrophi

Electrogenerated Bases. VI. Reaction of Electrogenerated Superoxide with Some Carbon Acids. II.

Electrogenerated superoxide and molecular oxygen were allowed to react sequentially with a number of esters, nitriles, N,N-dialkylamides, sulfones, and aliphatic nitro compounds.The α-methyl groups in these compounds bore aliphatic and/or aromatic substituents.When the electron-withdrawing group (EWG) of these carbon acids could be displaced intact (nitile 2, ArSO2 4, nitro) good to excellent yields of the corresponding carbonyl compounds could be obtained.The efficiency of the transformation depended upon the nature of the substituents: α,α-diphenyl (e.g., 2a) > α-methyl-α-phenyl (2b) > α,α-dimethyl.By conducting the electrolysis in the presence of acetic anhydride it was shown that the known conversion of phenylacetonitrile (2d) to benzoic acid did indeed proceed via benzaldehyde.When the EWG itself could be cleaved (esters 1, N,N-dialkyl-amides 3), this methodology produced α-hydroxylated compounds and the products resulting from fragmentation of the EWG and also from its complete displacement.The effects of the α-substituents were similar to those above.