10055-40-0

Basic information

• Product Name: (4-Aminophenyl)(4-fluorophenyl)methanone
• Synonyms: 4-[(4-Fluorophenyl)carbonyl]aniline;(4-Aminophenyl)(4-fluorophenyl)methanone
• CAS NO: 10055-40-0
• Molecular Formula: C₁₃H₁₀FNO
• Molecular Weight: 215.23
• Product Categories: Amines;Phenyls & Phenyl-Het
• Mol File: 10055-40-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 379.6±27.0 °C(Predicted)
• Appearance: /
• Density: 1.236±0.06 g/cm3(Predicted)
• PKA: 2.14±0.10(Predicted)
• CAS DataBase Reference: (4-Aminophenyl)(4-fluorophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Aminophenyl)(4-fluorophenyl)methanone(10055-40-0)
• EPA Substance Registry System: (4-Aminophenyl)(4-fluorophenyl)methanone(10055-40-0)

Safety Data

• Hazardous Substances Data: 10055-40-0(Hazardous Substances Data)

Usage

General Description

(4-Aminophenyl)(4-fluorophenyl)methanone is a chemical compound with the molecular formula C13H10FNO. It is a ketone derivative with a phenyl group substituted with both an amino group and a fluorine atom. (4-Aminophenyl)(4-fluorophenyl)methanone is of interest to researchers due to its potential applications in organic synthesis, medicinal chemistry, and pharmaceutical drug development. Its precise uses and properties have not been extensively studied, but it is likely to have potential as a building block in the synthesis of various organic compounds and as a drug candidate in the development of new pharmaceuticals. Further research is needed to fully elucidate the potential applications and properties of this compound.

Upstream product

• 2195-47-3 4-(4-fluorobenzoyl)-nitrobenzene 
• 462-06-6 fluorobenzene 
• 122-04-3 4-nitro-benzoyl chloride 
• 403-43-0 4-fluorobenzoyl chloride 
• 540-37-4 p-aminoiodobenzene 
• 62-53-3 aniline 
• 366-63-2 4-fluoro-N-phenylbenzamide 
• 459-56-3 4-fluorobenzylic alcohol 

Downstream Products

• 71970-06-4 C₂₆H₂₀F₂N₄ 
• 139442-21-0 N-[4-(4-fluorobenzoyl)phenyl]-5-ethylisoxazole-4-carboxamide 
• 1224702-82-2 4'-O-demethyl-4β-[4''-(4''-fluorobenzoyl)anilino]-4-desoxypodophyllotoxin 
• 1224702-76-4 4β-[4''-(4''-fluorobenzoyl)anilino]-4-desoxypodophyllotoxin 

Relevant articles and documents

Coumarin-surfactant modified polyoxometalate catalyzed cross dehydrogenative coupling of benzyl alcohol with the: Para -C-H of unprotected aniline

This paper presents a novel method for synthesizing para-aminobenzophenone and its derivatives (p-ABPs) using a coumarin-surfactant modified polyoxometalate as the catalyst. Preliminary mechanistic studies indicate that the reaction has undergone an oxidative cross dehydrogenative coupling process. This method has the advantages of an easy process, a convenient raw material source, safe and green oxidants, and tolerances of several functional groups.

Efficient Friedel–Crafts benzoylation of aniline derivatives with 4-fluorobenzoyl chloride using copper triflate in the synthesis of aminobenzophenones

ABSTRACT: An efficient pathway for the synthesis of the aminobenzophenone derivatives via Friedel–Crafts benzoylation using copper triflate as catalyst is proposed. New derivatives are synthesized. The copper triflate could be easily recovered and reused without loss of catalytic activity. Both the use of ionic liquids and microwave heating turned out to be fruitful.

Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities

A new class of 4β-N-polyaromatic substituted podophyllotoxin congeners have been synthesized and evaluated for their DNA topoisomerase-II (topo-II) inhibition as well as anticancer potential in some human cancer cell lines. The ease of synthesis and inter