100559-91-9

Basic information

• Product Name: 2,4-Bis(4-chlorphenyl)-6-oxo-6H-1,3-thiazin-5-carbonitril
• CAS NO: 100559-91-9
• Molecular Weight: 359.235
• Mol File: 100559-91-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,4-Bis(4-chlorphenyl)-6-oxo-6H-1,3-thiazin-5-carbonitril(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Bis(4-chlorphenyl)-6-oxo-6H-1,3-thiazin-5-carbonitril(100559-91-9)
• EPA Substance Registry System: 2,4-Bis(4-chlorphenyl)-6-oxo-6H-1,3-thiazin-5-carbonitril(100559-91-9)

Safety Data

• Hazardous Substances Data: 100559-91-9(Hazardous Substances Data)

Upstream product

• 159851-69-1 2,4-Bis(4-chlorphenyl)-6-thioxo-6H-1,3-thiazin-5-carbonitril 
• 36140-83-7 1-cyanoacetyl-3,5-dimethylpyrazole 

Downstream Products

• 159851-84-0 2,6-Bis(4-chlorphenyl)-3,4-dihydro-3-(2-hydroxyethyl)-4-oxopyrimidin-5-carbonitril 
• 159851-69-1 2,4-Bis(4-chlorphenyl)-6-thioxo-6H-1,3-thiazin-5-carbonitril 

Relevant articles and documents

Synthesis of N-Substituted Oxo- and Thioxopyrimidines from 1,2,4-Dithiazolium Salts

2,4-Diaryl-substituted 1,3-thiazine-5-carbonitriles 5, 6, obtained by reaction of 1,2,4-dithiazolium salts 1 with activated cyanoacetates, undergo ring transformations in the presence of primary and secondary amines.Thus, 5 and 6 react with primary amines under mild conditions to give hardly accessible N-3-substituted oxopyrimidine- or thioxopyrimidine-5-carbonitriles 11, 16, with secondary amines to give N-3-unsubstituted pyrimidine derivatives 14, 19 and with diamines to give imidazopyrimidines or pyrimidopyrimidines 23a, b.After alkylation of 1,3-thiazines 6, highly reactive 1,3-thiazinium salts 8 can be isolated. - Key Words: 1,3-Thiazines / Pyrimidines / Thiazinium salts